Osteoporosis

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Osteoporosis

Data are for the U.S.

Morbidity

Percent of men age 50 and older with osteoporosis of the femur neck or lumbar spine: 4.2% Percent of women age 50 and older with osteoporosis of the femur neck or lumbar spine: 18.8%

Source: Osteoporosis or Low Bone Mass in Older Adults: United States, 2017-2018

Related Links

National Health and Nutrition Examination Survey Bone Health & Osteoporosis | NIAMS Bone health and osteoporosis: a report of the Surgeon General

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Role of metabolites in mediating the effect of lipidomes on osteoporosis: A Mendelian randomization study.

We investigated the causal relationships between the plasma lipidomes, osteoporosis (OP), and potential metabolite mediators using Mendelian randomization (MR). Using summary-level data from a genome-wide association study, bidirectional MR analyses to explore the causal relationships between the plasma lipidomes and OP, and two-step MR to discover potential mediating metabolites. Sensitivity analyses were performed to validate the robustness of the results further. After primary analysis and a...

PubMed

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Summary Our findings suggest that although pregnancy and lactation are periods of physiological calcium loss, higher parity is not associated with an increased risk of postmenopausal osteoporosis; rather, it appears to confer a long-term protective effect. Purpose Osteoporosis is a significant public health burden. While parity induces transient bone loss, their long-term skeletal impact remains poorly understood. This study aimed to clarify the associations between parity, defined as the num...