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Nitrolingual (nitroglycerin)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Nitroglycerin, an organic nitrate, is a vasodilating agent.

USES: This medication is used to relieve chest pain (angina) in people that have a certain heart condition (coronary artery disease). It may also be used before physical activities (such as exercise, sexual activity) to help prevent chest pain. Nitroglycerin belongs to a class of drugs known as nitrates.

Angina occurs when the heart muscle is not getting enough blood. This drug works by relaxing and widening blood vessels so blood can flow more easily to the heart.

Generic name: nitroglycerin
Pronunciation: (NYE-troe-GLIS-er-in)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

Today’s intelligence on Nitrolingual

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Indications

The following indications are listed for Nitrolingual:

  • Acute Episode Of Anginal Pain
  • Pre-Exertional Prophylaxis Of Anginal Pain

Also known as: Acute Anginal Attack, Angina Attack, Anginal Attack, Pre-Exertion Prophylaxis Of Angina, Pre-Exertional Prevention Of Anginal Pain.

Dosing

Dosage of nitroglycerin must be carefully adjusted according to the patient's requirements and response and the smallest effective dosage should be used. When nitroglycerin is administered IV, the type of IV administration set used, polyvinyl chloride (PVC) or non-PVC, must be considered in dosage estimations. It should be noted that dosages commonly used in early published studies were based on the use of PVC administration sets and are too high when non-PVC administration sets are used.

Continuous monitoring of blood pressure and heart rate, as well as other appropriate parameters (e.g., pulmonary capillary wedge pressure), must be performed in all patients. Adequate systemic blood pressure and coronary perfusion pressure must be maintained. Some patients with normal or low left ventricular filling pressures or pulmonary capillary wedge pressure may be extremely sensitive to the effects of IV nitroglycerin and may respond fully to dosages as low as 5 mcg/minute; these patients require particularly careful monitoring and dosage titration.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

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Adverse reactions

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Precautions

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ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data