Kinevac (sincalide)
Injection Vial (Ea)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Sincalide, the synthetic C-terminal octapeptide of the hormone cholecystokinin (cholecystokinin-pancreozymin, pancreozymin), causes gallbladder contraction resulting in reduction of gallbladder size and in evacuation of bile.
Generic name: sincalide
Therapeutic class: Diagnostic Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Kinevac
Indications
The following indications are listed for Kinevac:
- Acceleration Of Barium Meal Transit Through The Small Bowel
- Diagnostic Aid For Biliary Tract
- Diagnostic Test For Pancreas Function
Also known as: Diagnostic Test For Pancreatic Insufficiency.
Dosing
The usual adult dose of sincalide to induce contraction of the gallbladder is 0.02 mcg/kg (1.4 mcg for a 70 kg adult). To prevent contraction of the neck of the gallbladder, the drug should be injected slowly over a 30- to 60-second period. If satisfactory contraction of the gallbladder does not occur in 15 minutes, a second dose of 0.04 mcg/kg may be administered.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Gastrointestinal obstruction
- Pregnancy
There are no severe contraindications for this drug.
- Choledocholithiasis
Adverse reactions
There is no enhanced messaging for this drug.
Less Frequent
- Seizure disorder
Rare or Very Rare
- Anaphylaxis
- Bradycardia
- Dyspnea
- Hypertension
- Hypotension
- Throat constriction
More Frequent
- Abdominal pain with cramps
- Acute abdominal pain
- Nausea
Less Frequent
- Diarrhea
- Dizziness
- Erythema
- Flushing
- Headache disorder
- Hyperhidrosis
- Hypoesthesia
- Sneezing
- Vomiting
Rare or Very Rare
- Fecal urgency
- Pruritus of skin
- Syncope
- Urticaria
Precautions
No enhanced messaging available.
No enhanced messaging available.
Safe use of sincalide during pregnancy has not been established.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Acceleration of barium meal transit through the small bowel | ||
| BD13YZZ | ICD10PCS | Fluoroscopy of small bowel using other contrast |
| Diagnostic aid for biliary tract | ||
| BF100ZZ | ICD10PCS | Fluoroscopy of bile ducts using high osmolar contrast |
| BF101ZZ | ICD10PCS | Fluoroscopy of bile ducts using low osmolar contrast |
| BF10YZZ | ICD10PCS | Fluoroscopy of bile ducts using other contrast |
| BF110ZZ | ICD10PCS | Fluoroscopy of biliary and pancreatic ducts using high osmolar contrast |
| BF111ZZ | ICD10PCS | Fluoroscopy of biliary and pancreatic ducts using low osmolar contrast |
| BF11YZZ | ICD10PCS | Fluoroscopy of biliary and pancreatic ducts using other contrast |
| BF120ZZ | ICD10PCS | Fluoroscopy of gallbladder using high osmolar contrast |
| BF121ZZ | ICD10PCS | Fluoroscopy of gallbladder using low osmolar contrast |
| BF12YZZ | ICD10PCS | Fluoroscopy of gallbladder using other contrast |
| BF130ZZ | ICD10PCS | Fluoroscopy of gallbladder and bile ducts using high osmolar contrast |
| BF131ZZ | ICD10PCS | Fluoroscopy of gallbladder and bile ducts using low osmolar contrast |
| BF13YZZ | ICD10PCS | Fluoroscopy of gallbladder and bile ducts using other contrast |
| BF140ZZ | ICD10PCS | Fluoroscopy of gallbladder, bile ducts and pancreatic ducts using high osmolar contrast |
| BF141ZZ | ICD10PCS | Fluoroscopy of gallbladder, bile ducts and pancreatic ducts using low osmolar contrast |
| BF14YZZ | ICD10PCS | Fluoroscopy of gallbladder, bile ducts and pancreatic ducts using other contrast |
| BF2C00Z | ICD10PCS | Computerized tomography (CT scan) of hepatobiliary system, all using high osmolar contrast, unenhanced and enhanced |
| BF2C0ZZ | ICD10PCS | Computerized tomography (CT scan) of hepatobiliary system, all using high osmolar contrast |
| BF2C10Z | ICD10PCS | Computerized tomography (CT scan) of hepatobiliary system, all using low osmolar contrast, unenhanced and enhanced |
| BF2C1ZZ | ICD10PCS | Computerized tomography (CT scan) of hepatobiliary system, all using low osmolar contrast |
| BF2CY0Z | ICD10PCS | Computerized tomography (CT scan) of hepatobiliary system, all using other contrast, unenhanced and enhanced |
| BF2CYZZ | ICD10PCS | Computerized tomography (CT scan) of hepatobiliary system, all using other contrast |
| BF2CZZZ | ICD10PCS | Computerized tomography (CT scan) of hepatobiliary system, all |
| Diagnostic test for pancreas function | ||
| 4A0B8GZ | ICD10PCS | Measurement of gastrointestinal secretion, via natural or artificial opening endoscopic |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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