Drug class

Agents to treat Thrombotic Thrombocytopenic Purpura (TTP)

Agents to treat thrombotic thrombocytopenic purpura (TTP) are an indication-based grouping of therapies rather than a single pharmacologic mechanism of action. Read more about Agents to treat Thrombotic Thrombocytopenic Purpura (TTP)

3 drugs in this class 2 manufacturers

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Drugs in Agents to treat Thrombotic Thrombocytopenic Purpura (TTP)

Showing 1–3 of 3 drugs

CABLIVI (caplacizumab-yhdp)

AGENTS TO TREAT THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) · ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA
GENZYME

CABLIVI (caplacizumab-yhdp)

AGENTS TO TREAT THROMBOTIC THROMBOCYTOPENIC PURPURA (TTP) · ACQUIRED THROMBOTIC THROMBOCYTOPENIC PURPURA
GENZYME
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About Agents to treat Thrombotic Thrombocytopenic Purpura (TTP).

Agents to treat thrombotic thrombocytopenic purpura (TTP) are an indication-based grouping of therapies rather than a single pharmacologic mechanism of action.

This therapeutic category encompasses targeted biological agents—most notably anti-von Willebrand factor directed nanobodies that prevent microvascular platelet aggregation, and recombinant ADAMTS13 enzyme replacement products—as well as systemic immunosuppressive agents that suppress anti-ADAMTS13 autoantibodies.

Used alongside therapeutic plasma exchange, these agents are indicated for the management and prevention of acute episodes of immune-mediated and congenital thrombotic thrombocytopenic purpura to alleviate thrombocytopenia, microangiopathic hemolytic anemia, and life-threatening systemic microvascular thrombosis.