Drug class

Aminosalicylic Acid

Although sometimes used to refer specifically to 4-aminosalicylic acid (an antimycobacterial agent used in tuberculosis) or to the 5-aminosalicylic acid chemical ingredient (mesalamine), the phrase "aminosalicylic acid" generally designates the aminosalicylate therapeutic drug class. Read more about Aminosalicylic Acid

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About Aminosalicylic Acid.

Although sometimes used to refer specifically to 4-aminosalicylic acid (an antimycobacterial agent used in tuberculosis) or to the 5-aminosalicylic acid chemical ingredient (mesalamine), the phrase "aminosalicylic acid" generally designates the aminosalicylate therapeutic drug class.

These agents are gastrointestinal anti-inflammatory medications that act primarily through local mucosal mechanisms, including inhibition of cyclooxygenase and lipoxygenase pathways, scavenging of free radicals, and activation of peroxisome proliferator-activated receptor-gamma (PPAR-?).

Clinically, drugs within this class—such as mesalamine, sulfasalazine, and balsalazide—serve as standard first-line therapies for the induction and maintenance of remission in mild-to-moderate inflammatory bowel disease, most notably ulcerative colitis.