Drug class
Anti-Inflammatory - Interleukin 1 Receptor Antagonist
The therapeutic class "Anti-Inflammatory - Interleukin 1 Receptor Antagonist" comprises biologic agents—most notably recombinant human interleukin-1 receptor antagonists such as anakinra—that selectively inhibit interleukin-1 (IL-1) signaling. Read more about Anti-Inflammatory - Interleukin 1 Receptor Antagonist
4 drugs in this class 3 manufacturers
Drugs in Anti-Inflammatory - Interleukin 1 Receptor Antagonist
ARCALYST (rilonacept)
ILARIS (PF) (canakinumab/PF)
ILARIS (canakinumab/PF)
The therapeutic class "Anti-Inflammatory - Interleukin 1 Receptor Antagonist" comprises biologic agents—most notably recombinant human interleukin-1 receptor antagonists such as anakinra—that selectively inhibit interleukin-1 (IL-1) signaling.
These agents exert their anti-inflammatory effects by competitively binding to the cell-surface interleukin-1 type I receptor (IL-1RI), thereby blocking the downstream proinflammatory cascades triggered by both IL-1a and IL-1ß.
Clinically, this drug class is utilized primarily to manage severe autoinflammatory and rheumatic conditions, including rheumatoid arthritis, cryopyrin-associated periodic syndromes, systemic juvenile idiopathic arthritis, and deficiency of the interleukin-1 receptor antagonist.
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nih.gov
The therapeutic class "Anti-Inflammatory - Interleukin 1 Receptor Antagonist" comprises biologic agents—most notably recombinant human interleukin-1 receptor antagonists such as anakinra—that selectively inhibit interleukin-1 (IL-1) signaling These agents exert their anti-inflammatory effects by competitively binding to the cell-surface interleukin-1 type I receptor (IL-1RI), thereby blocking the downstream proinflammatory cascades triggered by both IL-1α and IL-1β Clinically, this drug class is...
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nih.gov
The therapeutic class "Anti-Inflammatory - Interleukin 1 Receptor Antagonist" comprises biologic agents—most notably recombinant human interleukin-1 receptor antagonists such as anakinra—that selectively inhibit interleukin-1 (IL-1) signaling
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wikipedia.org
The therapeutic class "Anti-Inflammatory - Interleukin 1 Receptor Antagonist" comprises biologic agents—most notably recombinant human interleukin-1 receptor antagonists such as anakinra—that selectively inhibit interleukin-1 (IL-1) signaling Clinically, this drug class is utilized primarily to manage severe autoinflammatory and rheumatic conditions, including rheumatoid arthritis, cryopyrin-associated periodic syndromes, systemic juvenile idiopathic arthritis, and deficiency of the interleukin-...
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trialfriend.com
Clinically, this drug class is utilized primarily to manage severe autoinflammatory and rheumatic conditions, including rheumatoid arthritis, cryopyrin-associated periodic syndromes, systemic juvenile idiopathic arthritis, and deficiency of the interleukin-1 receptor antagonist
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