Drug class

Anti-Inflammatory - Interleukin 1 Receptor Antagonist

The therapeutic class "Anti-Inflammatory - Interleukin 1 Receptor Antagonist" comprises biologic agents—most notably recombinant human interleukin-1 receptor antagonists such as anakinra—that selectively inhibit interleukin-1 (IL-1) signaling. Read more about Anti-Inflammatory - Interleukin 1 Receptor Antagonist

4 drugs in this class 3 manufacturers

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Drugs in Anti-Inflammatory - Interleukin 1 Receptor Antagonist

Showing 1–4 of 4 drugs

ILARIS (canakinumab/PF)

ANTI-INFLAMMATORY - INTERLEUKIN 1 RECEPTOR ANTAGONIST · ACUTE GOUTY ARTHRITIS ·+7
Novartis Pharmaceuticals

ARCALYST (rilonacept)

ANTI-INFLAMMATORY - INTERLEUKIN 1 RECEPTOR ANTAGONIST · MUCKLE-WELLS SYNDROME ·+3
KINIKSA PHARMAC

ILARIS (canakinumab/PF)

ANTI-INFLAMMATORY - INTERLEUKIN 1 RECEPTOR ANTAGONIST · ACUTE GOUTY ARTHRITIS ·+7
Novartis Pharmaceuticals
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About Anti-Inflammatory - Interleukin 1 Receptor Antagonist.

The therapeutic class "Anti-Inflammatory - Interleukin 1 Receptor Antagonist" comprises biologic agents—most notably recombinant human interleukin-1 receptor antagonists such as anakinra—that selectively inhibit interleukin-1 (IL-1) signaling.

These agents exert their anti-inflammatory effects by competitively binding to the cell-surface interleukin-1 type I receptor (IL-1RI), thereby blocking the downstream proinflammatory cascades triggered by both IL-1a and IL-1ß.

Clinically, this drug class is utilized primarily to manage severe autoinflammatory and rheumatic conditions, including rheumatoid arthritis, cryopyrin-associated periodic syndromes, systemic juvenile idiopathic arthritis, and deficiency of the interleukin-1 receptor antagonist.