Drug class

Antimalarials - Artemisinin and Derivatives

Antimalarials – Artemisinin and Derivatives comprises a therapeutic class of fast-acting antiparasitic agents, including artemisinin, artesunate, artemether, and dihydroartemisinin. Read more about Antimalarials - Artemisinin and Derivatives

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Drugs in Antimalarials - Artemisinin and Derivatives

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ARTESUNATE

ANTIMALARIAL DRUGS · SEVERE MALARIA
AMIVAS, LLC
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About Antimalarials - Artemisinin and Derivatives.

Antimalarials – Artemisinin and Derivatives comprises a therapeutic class of fast-acting antiparasitic agents, including artemisinin, artesunate, artemether, and dihydroartemisinin.

These compounds exert their parasiticidal action via an essential endoperoxide bridge that undergoes iron- or heme-mediated cleavage within intraerythrocytic parasites, generating reactive free radicals that disrupt vital parasite proteins, organelles, and membrane transport systems.

Clinically, they are indicated for the prevention and treatment of *Plasmodium* infections, representing the core component of artemisinin-based combination therapies (ACTs) for uncomplicated falciparum malaria and intravenous regimens for severe malaria.