Drug class

Antineoplastic-Cytotoxic T-Lymp. antigen (CTLA-4),R-MC Antib

The classification string "Antineoplastic-Cytotoxic T-Lymp. Read more about Antineoplastic-Cytotoxic T-Lymp. antigen (CTLA-4),R-MC Antib

2 drugs in this class 2 manufacturers

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Drugs in Antineoplastic-Cytotoxic T-Lymp. antigen (CTLA-4),R-MC Antib

Showing 1–2 of 2 drugs

YERVOY (ipilimumab)

ANTINEOPLASTIC-CYTOTOXIC T-LYMP. ANTIGEN (CTLA-4),R-MC ANTIB · METASTATIC MALIGNANT MELANOMA ·+8
BMS PRIMARYCARE

IMJUDO (tremelimumab-actl)

ANTINEOPLASTIC-CYTOTOXIC T-LYMP. ANTIGEN (CTLA-4),R-MC ANTIB · LIVER CELL CARCINOMA ·+1
AstraZeneca Pharmaceuticals
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About Antineoplastic-Cytotoxic T-Lymp. antigen (CTLA-4),R-MC Antib.

The classification string "Antineoplastic-Cytotoxic T-Lymp.

antigen (CTLA-4),R-MC Antib" represents an administrative formulary heading denoting antineoplastic recombinant monoclonal antibodies targeting cytotoxic T-lymphocyte–associated antigen 4.

Biologically categorized as immune checkpoint inhibitors, these therapeutic antibodies—such as ipilimumab and tremelimumab—bind to CTLA-4 receptors on T cells to block inhibitory signals from CD80 and CD86 ligands, thereby disinhibiting and augmenting antitumor T-cell immune responses.

They are principally indicated for the treatment of advanced solid malignancies, including metastatic melanoma, non-small cell lung cancer, renal cell carcinoma, malignant pleural mesothelioma, and hepatocellular carcinoma, often administered either as monotherapy or in combination with other immunotherapeutic regimens.