Drug class

Antineoplastic - Photosensitizers

Antineoplastic photosensitizers are therapeutic agents used in photodynamic and photopheresis therapies that selectively accumulate in malignant or abnormal cells. Read more about Antineoplastic - Photosensitizers

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About Antineoplastic - Photosensitizers.

Antineoplastic photosensitizers are therapeutic agents used in photodynamic and photopheresis therapies that selectively accumulate in malignant or abnormal cells.

Upon activation by specific wavelengths of visible or near-infrared light, these compounds generate cytotoxic reactive oxygen species, such as singlet oxygen, leading to localized cellular apoptosis, necrosis, and targeted tumor tissue destruction.

Major indications include the palliation and ablation of non-small cell lung cancer, esophageal cancer, high-grade dysplasia in Barrett’s esophagus, superficial cutaneous malignancies, and cutaneous T-cell lymphoma.