Drug class
Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist
The antiviral-HIV CCR5 co-receptor antagonist class is a specialized group of antiretroviral entry inhibitors used in combination regimens to treat human immunodeficiency virus type 1 (HIV-1) infection. Read more about Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist
9 drugs in this class 7 manufacturers
Drugs in Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist
SELZENTRY (maraviroc)
MARAVIROC
SELZENTRY (maraviroc)
MARAVIROC
MARAVIROC
MARAVIROC
MARAVIROC
MARAVIROC
The antiviral-HIV CCR5 co-receptor antagonist class is a specialized group of antiretroviral entry inhibitors used in combination regimens to treat human immunodeficiency virus type 1 (HIV-1) infection.
Rather than targeting viral enzymes, these agents selectively bind to the host cell surface chemokine receptor CCR5, blocking its interaction with viral envelope glycoprotein gp120 and preventing CCR5-tropic virions from fusing with and entering host CD4 T cells.
This drug class is primarily indicated for patients with documented CCR5-tropic HIV-1, frequently serving as an essential therapeutic option for treatment-experienced individuals harboring viral strains resistant to other antiretroviral classes.
Because their activity is strictly receptor-dependent, they lack efficacy against CXCR4-tropic or dual-tropic viral strains.
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fda.gov
The antiviral-HIV CCR5 co-receptor antagonist class is a specialized group of antiretroviral entry inhibitors used in combination regimens to treat human immunodeficiency virus type 1 (HIV-1) infection
-
fda.gov
The antiviral-HIV CCR5 co-receptor antagonist class is a specialized group of antiretroviral entry inhibitors used in combination regimens to treat human immunodeficiency virus type 1 (HIV-1) infection Because their activity is strictly receptor-dependent, they lack efficacy against CXCR4-tropic or dual-tropic viral strains
-
fda.gov
Rather than targeting viral enzymes, these agents selectively bind to the host cell surface chemokine receptor CCR5, blocking its interaction with viral envelope glycoprotein gp120 and preventing CCR5-tropic virions from fusing with and entering host CD4 T cells Because their activity is strictly receptor-dependent, they lack efficacy against CXCR4-tropic or dual-tropic viral strains
-
nih.gov
Rather than targeting viral enzymes, these agents selectively bind to the host cell surface chemokine receptor CCR5, blocking its interaction with viral envelope glycoprotein gp120 and preventing CCR5-tropic virions from fusing with and entering host CD4 T cells
-
nih.gov
Rather than targeting viral enzymes, these agents selectively bind to the host cell surface chemokine receptor CCR5, blocking its interaction with viral envelope glycoprotein gp120 and preventing CCR5-tropic virions from fusing with and entering host CD4 T cells
-
fda.gov
This drug class is primarily indicated for patients with documented CCR5-tropic HIV-1, frequently serving as an essential therapeutic option for treatment-experienced individuals harboring viral strains resistant to other antiretroviral classes
-
fda.gov
This drug class is primarily indicated for patients with documented CCR5-tropic HIV-1, frequently serving as an essential therapeutic option for treatment-experienced individuals harboring viral strains resistant to other antiretroviral classes Because their activity is strictly receptor-dependent, they lack efficacy against CXCR4-tropic or dual-tropic viral strains
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