Drug class

Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist

The antiviral-HIV CCR5 co-receptor antagonist class is a specialized group of antiretroviral entry inhibitors used in combination regimens to treat human immunodeficiency virus type 1 (HIV-1) infection. Read more about Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist

9 drugs in this class 7 manufacturers

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Drugs in Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist

Showing 1–9 of 9 drugs

SELZENTRY (maraviroc)

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
VIIV HEALTHCARE

SELZENTRY (maraviroc)

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
VIIV HEALTHCARE

MARAVIROC

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
CAMBER PHARMACE

SELZENTRY (maraviroc)

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
A-S MEDICATION

MARAVIROC

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
I3 PHARMACEUTIC

MARAVIROC

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
XLCARE PHARMACE

MARAVIROC

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
A2A INTEGRATED

MARAVIROC

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
ZYDUS PHARMACEU

MARAVIROC

ANTIVIRAL-HIV (ANTIRETROVIRAL) CCR5 CO-RECEPTOR ANTAGONIST · CCR5 TROPIC HIV INFECTION
A-S MEDICATION
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About Antiviral-HIV (Antiretroviral) CCR5 Co-Receptor Antagonist.

The antiviral-HIV CCR5 co-receptor antagonist class is a specialized group of antiretroviral entry inhibitors used in combination regimens to treat human immunodeficiency virus type 1 (HIV-1) infection.

Rather than targeting viral enzymes, these agents selectively bind to the host cell surface chemokine receptor CCR5, blocking its interaction with viral envelope glycoprotein gp120 and preventing CCR5-tropic virions from fusing with and entering host CD4 T cells.

This drug class is primarily indicated for patients with documented CCR5-tropic HIV-1, frequently serving as an essential therapeutic option for treatment-experienced individuals harboring viral strains resistant to other antiretroviral classes.

Because their activity is strictly receptor-dependent, they lack efficacy against CXCR4-tropic or dual-tropic viral strains.