Drug class

Botulism Antitoxin

Botulism antitoxins are a class of passive immunizing biological agents containing specific polyclonal antibody fragments or immunoglobulins directed against neurotoxins produced by *Clostridium botulinum*. Read more about Botulism Antitoxin

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About Botulism Antitoxin.

Botulism antitoxins are a class of passive immunizing biological agents containing specific polyclonal antibody fragments or immunoglobulins directed against neurotoxins produced by *Clostridium botulinum*.

They function by binding to and neutralizing circulating, unattached botulinum neurotoxins in the bloodstream, preventing the toxins from entering presynaptic cholinergic nerve terminals and thereby halting the progression of neuromuscular paralysis.

These agents are indicated for the urgent treatment of symptomatic foodborne, wound, inhalational, or other forms of botulism in adult and pediatric populations.

Because they cannot displace toxins already bound to nerve endings or reverse established paralysis, prompt administration alongside intensive supportive care is essential to mitigate further neurotoxicity.