Drug class

C1 Esterase Inhibitors (Prophylaxis)

C1 esterase inhibitors for prophylaxis comprise a therapeutic class of plasma-derived protein replacement therapies indicated for routine, long-term prevention of recurrent angioedema attacks in patients with hereditary angioedema. Read more about C1 Esterase Inhibitors (Prophylaxis)

3 drugs in this class 3 manufacturers

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Drugs in C1 Esterase Inhibitors (Prophylaxis)

Showing 1–3 of 3 drugs

CINRYZE (C1 esterase inhibitor)

C1 ESTERASE INHIBITORS (PROPHYLAXIS) · PREVENTION OF ANGIOEDEMA ATTACKS IN PATIENT WITH HEREDITARY ANGIOEDEMA
MILLENNIUM PHAR

CINRYZE (C1 esterase inhibitor)

C1 ESTERASE INHIBITORS (PROPHYLAXIS) · PREVENTION OF ANGIOEDEMA ATTACKS IN PATIENT WITH HEREDITARY ANGIOEDEMA
Takeda Pharmaceuticals America
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About C1 Esterase Inhibitors (Prophylaxis).

C1 esterase inhibitors for prophylaxis comprise a therapeutic class of plasma-derived protein replacement therapies indicated for routine, long-term prevention of recurrent angioedema attacks in patients with hereditary angioedema.

Hereditary angioedema is an autosomal dominant disorder characterized by a quantitative deficiency or functional dysfunction of endogenous C1 esterase inhibitor.

These replacement agents function by replenishing functional levels of the serpin C1 inhibitor, thereby restoring physiological regulation over the complement, contact, and fibrinolytic cascades.

By inhibiting key serine proteases such as plasma kallikrein and activated factor XII, they suppress the excessive generation of bradykinin, effectively preventing bradykinin-mediated vasodilation, increased vascular permeability, and subcutaneous or submucosal swelling attacks.