Drug class

Collagenase Enzymes, Injectable

Injectable collagenase enzymes represent a targeted pharmacologic class of locally administered endopeptidases, most notably derived from *Clostridium histolyticum*. Read more about Collagenase Enzymes, Injectable

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About Collagenase Enzymes, Injectable.

Injectable collagenase enzymes represent a targeted pharmacologic class of locally administered endopeptidases, most notably derived from *Clostridium histolyticum*.

These biologic agents function through enzymatic fasciotomy or plaque disruption, selectively cleaving native triple-helical collagen to break down pathological fibrous cords and scar tissue.

In clinical practice, they provide nonsurgical intervention for localized fibroproliferative disorders, primarily adult Dupuytren contracture with a palpable cord and Peyronie disease characterized by a palpable penile plaque and curvature deformity.