Drug class

Cystic Fibrosis - Osmotic Agents Inhaled

Inhaled osmotic agents for cystic fibrosis represent a therapeutic drug class formulated to improve mucociliary clearance in the respiratory tract. Read more about Cystic Fibrosis - Osmotic Agents Inhaled

2 drugs in this class 2 manufacturers

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Drugs in Cystic Fibrosis - Osmotic Agents Inhaled

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BRONCHITOL (mannitol)

CYSTIC FIBROSIS - OSMOTIC AGENTS INHALED · RESPIRATORY CYSTIC FIBROSIS
CHIESI USA, INC

BRONCHITOL (mannitol)

CYSTIC FIBROSIS - OSMOTIC AGENTS INHALED · RESPIRATORY CYSTIC FIBROSIS
ARNA PHARMA PTY
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About Cystic Fibrosis - Osmotic Agents Inhaled.

Inhaled osmotic agents for cystic fibrosis represent a therapeutic drug class formulated to improve mucociliary clearance in the respiratory tract.

These agents, primarily including inhaled dry-powder mannitol and nebulized hypertonic saline, function by generating an osmotic gradient across the bronchial epithelium that draws water into the airway lumen.

This influx hydrates the airway surface liquid and reduces the viscoelasticity of abnormally thick secretions, thereby facilitating sputum expectoration, improving pulmonary function, and decreasing pulmonary exacerbations.

Accordingly, this class is utilized as maintenance therapy to manage chronic suppurative airway disease in patients with cystic fibrosis.