Drug class

Cytomegalovirus (CMV) Immune Globulin

Cytomegalovirus (CMV) immune globulin refers to a therapeutic class of hyperimmune globulins prepared from pooled human plasma selected for high titers of neutralizing antibodies against cytomegalovirus. Read more about Cytomegalovirus (CMV) Immune Globulin

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About Cytomegalovirus (CMV) Immune Globulin.

Cytomegalovirus (CMV) immune globulin refers to a therapeutic class of hyperimmune globulins prepared from pooled human plasma selected for high titers of neutralizing antibodies against cytomegalovirus.

It provides targeted passive immunity by binding and neutralizing viral particles, thereby reducing viral load and mitigating CMV-mediated cellular damage.

Clinically, this biologic class is primarily used for the prophylaxis and attenuation of cytomegalovirus disease in immunosuppressed individuals, most notably solid organ transplant recipients (such as kidney, lung, liver, pancreas, and heart).

In clinical practice, it is often administered either alone or in combination with antiviral therapies to protect high-risk patient populations, such as seronegative recipients receiving organs from seropositive donors.