Drug class
Dactinomycin
Dactinomycin (also known as actinomycin D) is a specific active drug substance rather than an entire broad therapeutic class; pharmacologically, it belongs to the actinomycin subclass of cytotoxic, antineoplastic antibiotics. Read more about Dactinomycin
5 drugs in this class 5 manufacturers
Drugs in Dactinomycin
DACTINOMYCIN
DACTINOMYCIN
DACTINOMYCIN
DACTINOMYCIN
Dactinomycin (also known as actinomycin D) is a specific active drug substance rather than an entire broad therapeutic class; pharmacologically, it belongs to the actinomycin subclass of cytotoxic, antineoplastic antibiotics.
It exerts its antineoplastic effects primarily by intercalating between adjacent guanine-cytosine base pairs of DNA, which inhibits RNA synthesis by blocking RNA polymerase elongation and impedes subsequent protein production.
Therapeutically, dactinomycin is used as an essential component of chemotherapy regimens to treat pediatric and adult solid malignancies, including Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, metastatic nonseminomatous testicular cancer, and gestational trophoblastic neoplasia.
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fda.gov
Dactinomycin (also known as actinomycin D) is a specific active drug substance rather than an entire broad therapeutic class; pharmacologically, it belongs to the actinomycin subclass of cytotoxic, antineoplastic antibiotics
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nih.gov
Dactinomycin (also known as actinomycin D) is a specific active drug substance rather than an entire broad therapeutic class; pharmacologically, it belongs to the actinomycin subclass of cytotoxic, antineoplastic antibiotics
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cancer.gov
It exerts its antineoplastic effects primarily by intercalating between adjacent guanine-cytosine base pairs of DNA, which inhibits RNA synthesis by blocking RNA polymerase elongation and impedes subsequent protein production
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drugbank.com
It exerts its antineoplastic effects primarily by intercalating between adjacent guanine-cytosine base pairs of DNA, which inhibits RNA synthesis by blocking RNA polymerase elongation and impedes subsequent protein production
-
fda.gov
Therapeutically, dactinomycin is used as an essential component of chemotherapy regimens to treat pediatric and adult solid malignancies, including Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, metastatic nonseminomatous testicular cancer, and gestational trophoblastic neoplasia
-
nih.gov
Therapeutically, dactinomycin is used as an essential component of chemotherapy regimens to treat pediatric and adult solid malignancies, including Wilms tumor, rhabdomyosarcoma, Ewing sarcoma, metastatic nonseminomatous testicular cancer, and gestational trophoblastic neoplasia
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