TRETTEN (factor XIII A-subunit, recombinant)
FACTOR XIII · HEREDITARY FACTOR XIII A SUBUNIT DEFICIENCY
NOVO NORDISK
Drug class
Factor XIII
Factor XIII (often referred to clinically as Factor XIII concentrates or replacement products) represents a specialized group of biologic hemostatic agents within the broader coagulation factor replacement class. Read more about Factor XIII
2 drugs in this class 2 manufacturers
Drugs in Factor XIII
CORIFACT (factor XIII)
FACTOR XIII · HEREDITARY FACTOR XIII DEFICIENCY DISEASE
CSL Behring
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Factor XIII (often referred to clinically as Factor XIII concentrates or replacement products) represents a specialized group of biologic hemostatic agents within the broader coagulation factor replacement class.
These agents—available as human plasma-derived concentrates or recombinant Factor XIII A-subunit formulations—work by supplying exogenous transglutaminase to restore adequate blood levels of the final enzyme in the coagulation cascade.
Upon activation by thrombin and calcium, Factor XIII cross-links fibrin monomers and incorporates antifibrinolytic proteins into developing clots, mechanically stabilizing the hemostatic plug and preventing premature fibrinolysis.
Therapeutically, this class is primarily utilized for routine bleeding prophylaxis and perioperative surgical management in adult and pediatric patients with rare congenital Factor XIII deficiencies.
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drugs.com
Factor XIII (often referred to clinically as Factor XIII concentrates or replacement products) represents a specialized group of biologic hemostatic agents within the broader coagulation factor replacement class These agents—available as human plasma-derived concentrates or recombinant Factor XIII A-subunit formulations—work by supplying exogenous transglutaminase to restore adequate blood levels of the final enzyme in the coagulation cascade
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drugbank.com
Factor XIII (often referred to clinically as Factor XIII concentrates or replacement products) represents a specialized group of biologic hemostatic agents within the broader coagulation factor replacement class These agents—available as human plasma-derived concentrates or recombinant Factor XIII A-subunit formulations—work by supplying exogenous transglutaminase to restore adequate blood levels of the final enzyme in the coagulation cascade Upon activation by thrombin and calcium, Factor XIII ...
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fda.gov
These agents—available as human plasma-derived concentrates or recombinant Factor XIII A-subunit formulations—work by supplying exogenous transglutaminase to restore adequate blood levels of the final enzyme in the coagulation cascade Therapeutically, this class is primarily utilized for routine bleeding prophylaxis and perioperative surgical management in adult and pediatric patients with rare congenital Factor XIII deficiencies
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fda.gov
Therapeutically, this class is primarily utilized for routine bleeding prophylaxis and perioperative surgical management in adult and pediatric patients with rare congenital Factor XIII deficiencies
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