Drug class
Gold Compounds
Gold compounds, also referred to as gold salts or chrysotherapy agents, are a historic class of disease-modifying antirheumatic drugs (DMARDs) composed of organic complexes containing gold. Read more about Gold Compounds
4 drugs in this class 4 manufacturers
Drugs in Gold Compounds
AURANOFIN
RIDAURA (auranofin)
AURANOFIN
Gold compounds, also referred to as gold salts or chrysotherapy agents, are a historic class of disease-modifying antirheumatic drugs (DMARDs) composed of organic complexes containing gold.
They exert immunomodulatory and anti-inflammatory effects by altering macrophage function, suppressing lysosomal enzyme release, interfering with antigen processing, and downregulating pro-inflammatory cytokine expression.
Historically, oral and injectable agents within this class, such as auranofin and gold sodium thiomalate, served as foundational therapies to reduce synovitis and slow radiographic joint damage in progressive autoimmune disorders, principally rheumatoid arthritis and juvenile idiopathic arthritis.
Although their modern clinical use has largely been superseded by more effective and less toxic biologic and synthetic DMARDs, they remain a recognized pharmacological class for refractory inflammatory arthropathies.
-
nih.gov
Gold compounds, also referred to as gold salts or chrysotherapy agents, are a historic class of disease-modifying antirheumatic drugs (DMARDs) composed of organic complexes containing gold Historically, oral and injectable agents within this class, such as auranofin and gold sodium thiomalate, served as foundational therapies to reduce synovitis and slow radiographic joint damage in progressive autoimmune disorders, principally rheumatoid arthritis and juvenile idiopathic arthritis Although thei...
-
nih.gov
Gold compounds, also referred to as gold salts or chrysotherapy agents, are a historic class of disease-modifying antirheumatic drugs (DMARDs) composed of organic complexes containing gold Historically, oral and injectable agents within this class, such as auranofin and gold sodium thiomalate, served as foundational therapies to reduce synovitis and slow radiographic joint damage in progressive autoimmune disorders, principally rheumatoid arthritis and juvenile idiopathic arthritis
-
nih.gov
They exert immunomodulatory and anti-inflammatory effects by altering macrophage function, suppressing lysosomal enzyme release, interfering with antigen processing, and downregulating pro-inflammatory cytokine expression
-
nih.gov
They exert immunomodulatory and anti-inflammatory effects by altering macrophage function, suppressing lysosomal enzyme release, interfering with antigen processing, and downregulating pro-inflammatory cytokine expression
-
nih.gov
Although their modern clinical use has largely been superseded by more effective and less toxic biologic and synthetic DMARDs, they remain a recognized pharmacological class for refractory inflammatory arthropathies
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