Human Papillomavirus (HPV) Vaccines

Human Papillomavirus (HPV) Vaccines are an immunologic class of prophylactic biological agents composed of non-infectious, recombinant virus-like particles derived from viral L1 capsid proteins They function by eliciting high titers of neutralizing antibodies against targeted high-risk and low-risk human papillomavirus serotypes, blocking initial viral entry and preventing persistent mucosal and cutaneous infection Clinically, these vaccines are primarily utilized to prevent HPV-associated malig...

They function by eliciting high titers of neutralizing antibodies against targeted high-risk and low-risk human papillomavirus serotypes, blocking initial viral entry and preventing persistent mucosal and cutaneous infection Clinically, these vaccines are primarily utilized to prevent HPV-associated malignancies—including cervical, vaginal, vulvar, anal, and head and neck or oropharyngeal cancers—as well as associated precancerous intraepithelial dysplasias and benign anogenital warts