CAYSTON (aztreonam lysine)
INHALED MONOBACTAMS · RESPIRATORY CYSTIC FIBROSIS WITH PSEUDOMONAS AERUGINOSA COLONIZATION
GILEAD SCIENCES
Drug class
Inhaled Monobactams
Inhaled monobactams are aerosolized formulations of monocyclic beta-lactam antibacterial agents, primarily represented in clinical practice by inhaled aztreonam (aztreonam lysine). Read more about Inhaled Monobactams
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Drugs in Inhaled Monobactams
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Inhaled monobactams are aerosolized formulations of monocyclic beta-lactam antibacterial agents, primarily represented in clinical practice by inhaled aztreonam (aztreonam lysine).
They exert bactericidal activity by selectively binding to penicillin-binding protein 3 (PBP3) in susceptible Gram-negative bacteria, thereby blocking bacterial cell wall synthesis and causing cell lysis while delivering high drug concentrations directly to endobronchial spaces with minimal systemic exposure.
This drug class is primarily indicated for patients with cystic fibrosis to treat chronic endobronchial infections caused by *Pseudomonas aeruginosa*, helping to suppress bacterial burden, improve respiratory symptoms, and preserve pulmonary function.
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wellfleetrx.com
Inhaled monobactams are aerosolized formulations of monocyclic beta-lactam antibacterial agents, primarily represented in clinical practice by inhaled aztreonam (aztreonam lysine)
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nih.gov
Inhaled monobactams are aerosolized formulations of monocyclic beta-lactam antibacterial agents, primarily represented in clinical practice by inhaled aztreonam (aztreonam lysine) This drug class is primarily indicated for patients with cystic fibrosis to treat chronic endobronchial infections caused by *Pseudomonas aeruginosa*, helping to suppress bacterial burden, improve respiratory symptoms, and preserve pulmonary function
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merckmanuals.com
Inhaled monobactams are aerosolized formulations of monocyclic beta-lactam antibacterial agents, primarily represented in clinical practice by inhaled aztreonam (aztreonam lysine)
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drugbank.com
They exert bactericidal activity by selectively binding to penicillin-binding protein 3 (PBP3) in susceptible Gram-negative bacteria, thereby blocking bacterial cell wall synthesis and causing cell lysis while delivering high drug concentrations directly to endobronchial spaces with minimal systemic exposure
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patsnap.com
They exert bactericidal activity by selectively binding to penicillin-binding protein 3 (PBP3) in susceptible Gram-negative bacteria, thereby blocking bacterial cell wall synthesis and causing cell lysis while delivering high drug concentrations directly to endobronchial spaces with minimal systemic exposure
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mayoclinic.org
This drug class is primarily indicated for patients with cystic fibrosis to treat chronic endobronchial infections caused by *Pseudomonas aeruginosa*, helping to suppress bacterial burden, improve respiratory symptoms, and preserve pulmonary function
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