Drug class

Lymphocyte Immune Globulin

Lymphocyte immune globulin refers specifically to polyclonal antilymphocyte antibody preparations, most notably designated in official labeling as lymphocyte immune globulin, anti-thymocyte globulin. Read more about Lymphocyte Immune Globulin

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About Lymphocyte Immune Globulin.

Lymphocyte immune globulin refers specifically to polyclonal antilymphocyte antibody preparations, most notably designated in official labeling as lymphocyte immune globulin, anti-thymocyte globulin.

Acting as potent immunosuppressive biologics, these preparations contain concentrated immunoglobulin G raised against human lymphocytes, functioning primarily by binding surface antigens to deplete circulating T lymphocytes and suppress cell-mediated immune responses.

Therapeutically, they are primarily indicated for the management of acute allograft rejection in renal transplantation and the treatment of moderate-to-severe aplastic anemia in patients unsuitable for bone marrow transplantation.