LYSODREN (mitotane)
MITOTANE · ADRENAL CORTEX CARCINOMA
LABORATOIRE HRA
Drug class
Mitotane
Mitotane is an active drug substance rather than an overarching pharmacological class; clinically and regulatorily, it functions as an adrenal cytotoxic agent and antineoplastic adrenolytic therapy. Read more about Mitotane
2 drugs in this class 2 manufacturers
Drugs in Mitotane
LYSODREN (mitotane)
MITOTANE · ADRENAL CORTEX CARCINOMA
LAB HRA/ESTEVE
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Mitotane is an active drug substance rather than an overarching pharmacological class; clinically and regulatorily, it functions as an adrenal cytotoxic agent and antineoplastic adrenolytic therapy.
It acts by exerting direct cytotoxic effects on adrenocortical cells, inducing mitochondrial dysfunction, suppressing adrenal steroidogenesis, and altering the peripheral metabolism of corticosteroids.
Its primary therapeutic role is in oncology and endocrinology for the management of inoperable, metastatic, functional or nonfunctional adrenocortical carcinoma, and it is also utilized off-label in refractory Cushing's syndrome.
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fda.gov
Mitotane is an active drug substance rather than an overarching pharmacological class; clinically and regulatorily, it functions as an adrenal cytotoxic agent and antineoplastic adrenolytic therapy Its primary therapeutic role is in oncology and endocrinology for the management of inoperable, metastatic, functional or nonfunctional adrenocortical carcinoma, and it is also utilized off-label in refractory Cushing's syndrome
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nih.gov
Mitotane is an active drug substance rather than an overarching pharmacological class; clinically and regulatorily, it functions as an adrenal cytotoxic agent and antineoplastic adrenolytic therapy
-
fda.gov
It acts by exerting direct cytotoxic effects on adrenocortical cells, inducing mitochondrial dysfunction, suppressing adrenal steroidogenesis, and altering the peripheral metabolism of corticosteroids
-
patsnap.com
It acts by exerting direct cytotoxic effects on adrenocortical cells, inducing mitochondrial dysfunction, suppressing adrenal steroidogenesis, and altering the peripheral metabolism of corticosteroids
-
drugs.com
Its primary therapeutic role is in oncology and endocrinology for the management of inoperable, metastatic, functional or nonfunctional adrenocortical carcinoma, and it is also utilized off-label in refractory Cushing's syndrome
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