PRETOMANID
NITROIMIDAZOLE DERIVATIVES ANTI-MYCOBACTERIAL ANTIBIOTICS · PULMONARY MULTI-DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS
DEY LABS.
Drug class
Nitroimidazole Derivatives Anti-Mycobacterial Antibiotics
Nitroimidazole derivatives used as antimycobacterial antibiotics—most notably pretomanid and delamanid—are a specialized class of synthetic antibacterial prodrugs designed to combat mycobacterial infections. Read more about Nitroimidazole Derivatives Anti-Mycobacterial Antibiotics
2 drugs in this class 2 manufacturers
Drugs in Nitroimidazole Derivatives Anti-Mycobacterial Antibiotics
PRETOMANID
NITROIMIDAZOLE DERIVATIVES ANTI-MYCOBACTERIAL ANTIBIOTICS · PULMONARY MULTI-DRUG RESISTANT MYCOBACTERIUM TUBERCULOSIS
Viatris Specialty
Filter & compare in the drug finder →
Opens the drug finder with Nitroimidazole Derivatives Anti-Mycobacterial Antibiotics preselected. Add indication or manufacturer filters there.
Nitroimidazole derivatives used as antimycobacterial antibiotics—most notably pretomanid and delamanid—are a specialized class of synthetic antibacterial prodrugs designed to combat mycobacterial infections.
These agents undergo intracellular bioreductive activation by bacterial nitroreductases, which generates reactive nitrogen species that poison mycobacterial respiration and disrupt cell wall lipid synthesis, specifically mycolic acid production.
Consequently, they exhibit bactericidal activity against both actively replicating and non-replicating, hypoxic bacilli.
Clinically, these agents serve as vital components of combination chemotherapy regimens specifically for the treatment of multidrug-resistant and extensively drug-resistant pulmonary tuberculosis.
-
rhochistj.org
Nitroimidazole derivatives used as antimycobacterial antibiotics—most notably pretomanid and delamanid—are a specialized class of synthetic antibacterial prodrugs designed to combat mycobacterial infections These agents undergo intracellular bioreductive activation by bacterial nitroreductases, which generates reactive nitrogen species that poison mycobacterial respiration and disrupt cell wall lipid synthesis, specifically mycolic acid production Clinically, these agents serve as vital componen...
-
nih.gov
Nitroimidazole derivatives used as antimycobacterial antibiotics—most notably pretomanid and delamanid—are a specialized class of synthetic antibacterial prodrugs designed to combat mycobacterial infections
-
asm.org
Nitroimidazole derivatives used as antimycobacterial antibiotics—most notably pretomanid and delamanid—are a specialized class of synthetic antibacterial prodrugs designed to combat mycobacterial infections
-
nih.gov
These agents undergo intracellular bioreductive activation by bacterial nitroreductases, which generates reactive nitrogen species that poison mycobacterial respiration and disrupt cell wall lipid synthesis, specifically mycolic acid production Consequently, they exhibit bactericidal activity against both actively replicating and non-replicating, hypoxic bacilli
-
fda.gov
These agents undergo intracellular bioreductive activation by bacterial nitroreductases, which generates reactive nitrogen species that poison mycobacterial respiration and disrupt cell wall lipid synthesis, specifically mycolic acid production Consequently, they exhibit bactericidal activity against both actively replicating and non-replicating, hypoxic bacilli
-
patsnap.com
Consequently, they exhibit bactericidal activity against both actively replicating and non-replicating, hypoxic bacilli
-
wikipedia.org
Clinically, these agents serve as vital components of combination chemotherapy regimens specifically for the treatment of multidrug-resistant and extensively drug-resistant pulmonary tuberculosis
-
nih.gov
Clinically, these agents serve as vital components of combination chemotherapy regimens specifically for the treatment of multidrug-resistant and extensively drug-resistant pulmonary tuberculosis
Sign in to follow this class
Following a drug class requires a free Physicians Office Resource account.