Drug class

Ophthalmic Antifungals

Ophthalmic antifungals are a specialized class of topical anti-infective formulations administered directly to ocular tissues to eradicate or suppress pathogenic fungi. Read more about Ophthalmic Antifungals

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About Ophthalmic Antifungals.

Ophthalmic antifungals are a specialized class of topical anti-infective formulations administered directly to ocular tissues to eradicate or suppress pathogenic fungi.

They primarily function by disrupting fungal cell membrane integrity—such as polyenes binding directly to ergosterol or azoles inhibiting ergosterol biosynthesis—which induces cell permeability and fungal death.

In clinical ophthalmology, this therapeutic class is indicated for superficial and invasive ocular mycoses, most notably fungal keratitis, blepharitis, and conjunctivitis caused by organisms such as *Fusarium*, *Aspergillus*, and *Candida*.