Drug class
Psoralens, Systemic
Systemic psoralens are orally administered furocoumarin photosensitizers used in photochemotherapy regimens alongside controlled ultraviolet A radiation, commonly known as PUVA therapy. Read more about Psoralens, Systemic
3 drugs in this class 2 manufacturers
Drugs in Psoralens, Systemic
METHOXSALEN (methoxsalen, rapid)
METHOXSALEN
Systemic psoralens are orally administered furocoumarin photosensitizers used in photochemotherapy regimens alongside controlled ultraviolet A radiation, commonly known as PUVA therapy.
Following systemic absorption and distribution to the skin, these compounds intercalate into cellular DNA; subsequent UVA exposure activates them to form interstrand cross-links and monoadducts with pyrimidine bases, thereby inhibiting DNA synthesis, suppressing rapid cellular proliferation, and exerting localized immunomodulatory effects.
Systemic psoralens, represented predominantly by methoxsalen, are indicated for the management of severe, recalcitrant psoriasis, extensive vitiligo, and cutaneous T-cell lymphoma, such as mycosis fungoides.
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fda.gov
Systemic psoralens are orally administered furocoumarin photosensitizers used in photochemotherapy regimens alongside controlled ultraviolet A radiation, commonly known as PUVA therapy Systemic psoralens, represented predominantly by methoxsalen, are indicated for the management of severe, recalcitrant psoriasis, extensive vitiligo, and cutaneous T-cell lymphoma, such as mycosis fungoides
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nih.gov
Systemic psoralens are orally administered furocoumarin photosensitizers used in photochemotherapy regimens alongside controlled ultraviolet A radiation, commonly known as PUVA therapy
-
nih.gov
Following systemic absorption and distribution to the skin, these compounds intercalate into cellular DNA; subsequent UVA exposure activates them to form interstrand cross-links and monoadducts with pyrimidine bases, thereby inhibiting DNA synthesis, suppressing rapid cellular proliferation, and exerting localized immunomodulatory effects
-
nih.gov
Following systemic absorption and distribution to the skin, these compounds intercalate into cellular DNA; subsequent UVA exposure activates them to form interstrand cross-links and monoadducts with pyrimidine bases, thereby inhibiting DNA synthesis, suppressing rapid cellular proliferation, and exerting localized immunomodulatory effects Systemic psoralens, represented predominantly by methoxsalen, are indicated for the management of severe, recalcitrant psoriasis, extensive vitiligo, and cutan...
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bcbsfl.com
Systemic psoralens, represented predominantly by methoxsalen, are indicated for the management of severe, recalcitrant psoriasis, extensive vitiligo, and cutaneous T-cell lymphoma, such as mycosis fungoides
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