ELLA (ulipristal acetate)
CONTRACEPTIVES · POSTCOITAL CONTRACEPTION
HRA PHARMA AMER
Drug class
Selective Progesterone-Receptor Modulators
Selective progesterone-receptor modulators (SPRMs) are a pharmacologic class of synthetic steroid ligands that interact directly with progesterone receptors to exert tissue-specific agonist, antagonist, or mixed agonist-antagonist biological effects. Read more about Selective Progesterone-Receptor Modulators
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Selective progesterone-receptor modulators (SPRMs) are a pharmacologic class of synthetic steroid ligands that interact directly with progesterone receptors to exert tissue-specific agonist, antagonist, or mixed agonist-antagonist biological effects.
By selectively modulating progesterone signaling pathways in target reproductive tissues, these agents inhibit ovulation, suppress endometrial proliferation, and reduce abnormal bleeding without inducing systemic hypoestrogenism.
Clinically, members of this class—such as ulipristal acetate and mifepristone—are primarily utilized for emergency contraception, the medical management of symptomatic uterine leiomyomas (fibroids), and early pregnancy termination.
They have also been investigated for therapeutic application in endometriosis and hormone-receptor-positive breast malignancies.
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nih.gov
Selective progesterone-receptor modulators (SPRMs) are a pharmacologic class of synthetic steroid ligands that interact directly with progesterone receptors to exert tissue-specific agonist, antagonist, or mixed agonist-antagonist biological effects Clinically, members of this class—such as ulipristal acetate and mifepristone—are primarily utilized for emergency contraception, the medical management of symptomatic uterine leiomyomas (fibroids), and early pregnancy termination They have also been...
-
nih.gov
Selective progesterone-receptor modulators (SPRMs) are a pharmacologic class of synthetic steroid ligands that interact directly with progesterone receptors to exert tissue-specific agonist, antagonist, or mixed agonist-antagonist biological effects They have also been investigated for therapeutic application in endometriosis and hormone-receptor-positive breast malignancies
-
nih.gov
By selectively modulating progesterone signaling pathways in target reproductive tissues, these agents inhibit ovulation, suppress endometrial proliferation, and reduce abnormal bleeding without inducing systemic hypoestrogenism
-
nih.gov
By selectively modulating progesterone signaling pathways in target reproductive tissues, these agents inhibit ovulation, suppress endometrial proliferation, and reduce abnormal bleeding without inducing systemic hypoestrogenism
-
nih.gov
Clinically, members of this class—such as ulipristal acetate and mifepristone—are primarily utilized for emergency contraception, the medical management of symptomatic uterine leiomyomas (fibroids), and early pregnancy termination
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