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Drug class

Smallpox Vaccine

Smallpox vaccines are an immunobiologic drug class comprising live viral vaccines derived from the vaccinia virus, available in both replication-competent formulations (such as ACAM2000) and non-replicating attenuated formulations (such as JYNNEOS). Read more about Smallpox Vaccine

5 drugs in this class 2 manufacturers

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Drugs in Smallpox Vaccine

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About Smallpox Vaccine.

Smallpox vaccines are an immunobiologic drug class comprising live viral vaccines derived from the vaccinia virus, available in both replication-competent formulations (such as ACAM2000) and non-replicating attenuated formulations (such as JYNNEOS).

They function by stimulating humoral and cellular immune responses that elicit cross-protective neutralizing antibodies and T-cell immunity against antigens shared among orthopoxviruses.

Because the variola virus has been eradicated, this class is primarily utilized for biodefense preparedness, protection of laboratory and healthcare personnel at occupational risk, and the prevention and post-exposure prophylaxis of smallpox and related orthopoxvirus infections, notably mpox.