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Gentamicin (gentamicin sulfate)

Topical Antibiotics Topical Ointment (Gram)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Gentamicin is an aminoglycoside antibiotic.

Gentamicin is used topically in the treatment of superficial infections of the skin caused by susceptible bacteria. However, substantial evidence of effectiveness is lacking and some experts question the use of topical antibiotics in general. Minor skin infections and wounds usually heal without treatment, and systemic anti-infective therapy is required for the treatment of serious or extensive skin infections.

In addition, indiscriminate use of topical gentamicin may result in the emergence of organisms resistant to the drug and other aminoglycosides.

Generic name: gentamicin sulfate
Pronunciation: (JEN-ta-MYE-sin)
Drug class: Topical Antibiotics
Therapeutic class: Dermatological

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

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Indications

The following indications are listed for Gentamicin:

  • Bacterial Skin And Skin Structure Infection
  • Folliculitis
  • Furunculosis
  • Paronychia

Also known as: Bacterial Skin Infection, Furuncle, Onychia Lateralis, Onychia Periungualis, Perionychia, Perionyxis.

Dosing

Gentamicin sulfate is applied topically to the skin in the form of a cream or ointment containing 0.1% gentamicin. Because the ointment helps retain moisture, it has been used in the treatment of infections on dry, eczematous, or psoriatic skin. The cream is usually used for the treatment of wet, oozing primary infections and greasy secondary infections; the cream is also used if a water-washable preparation is desired.

A small amount of gentamicin cream or ointment should be applied gently to the cleansed affected area 3-4 times daily. The area may be covered with a sterile gauze dressing; infected stasis ulcers may be covered with gelatin packing. In the topical treatment of impetigo, crusts should be removed from the lesions to permit contact between the antibiotic and the infection. Care should be taken to avoid further contamination of the infected skin.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

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Adverse reactions

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Precautions

No enhanced messaging available.

ICD codes

CodeTypeDescription
Bacterial skin and skin structure infection
H60.1ICD10CMCellulitis of external ear
H60.10ICD10CMCellulitis of external ear, unspecified ear
H60.11ICD10CMCellulitis of right external ear
H60.12ICD10CMCellulitis of left external ear
H60.13ICD10CMCellulitis of external ear, bilateral
L01.00ICD10CMImpetigo, unspecified
L01.03ICD10CMBullous impetigo
L02.02ICD10CMFuruncle of face
L02.03ICD10CMCarbuncle of face
L02.12ICD10CMFuruncle of neck
L02.13ICD10CMCarbuncle of neck
L02.217ICD10CMCutaneous abscess of flank
L02.221ICD10CMFuruncle of abdominal wall
L02.222ICD10CMFuruncle of back [any part, except buttock and flank]
L02.223ICD10CMFuruncle of chest wall
L02.224ICD10CMFuruncle of groin
L02.225ICD10CMFuruncle of perineum
L02.226ICD10CMFuruncle of umbilicus
L02.229ICD10CMFuruncle of trunk, unspecified
L02.231ICD10CMCarbuncle of abdominal wall
L02.232ICD10CMCarbuncle of back [any part, except buttock and flank]
L02.233ICD10CMCarbuncle of chest wall
L02.234ICD10CMCarbuncle of groin
L02.235ICD10CMCarbuncle of perineum
L02.236ICD10CMCarbuncle of umbilicus
L02.237ICD10CMCarbuncle of flank
L02.239ICD10CMCarbuncle of trunk, unspecified
L02.33ICD10CMCarbuncle of buttock
L02.429ICD10CMFuruncle of limb, unspecified
L02.439ICD10CMCarbuncle of limb, unspecified
L02.529ICD10CMFuruncle unspecified hand
L02.539ICD10CMCarbuncle of unspecified hand
L02.629ICD10CMFuruncle of unspecified foot
L02.639ICD10CMCarbuncle of unspecified foot
L02.821ICD10CMFuruncle of head [any part, except face]
L02.828ICD10CMFuruncle of other sites
L02.831ICD10CMCarbuncle of head [any part, except face]
L02.838ICD10CMCarbuncle of other sites
L02.92ICD10CMFuruncle, unspecified
L02.93ICD10CMCarbuncle, unspecified
L03.01ICD10CMCellulitis of finger
L03.011ICD10CMCellulitis of right finger
L03.012ICD10CMCellulitis of left finger
L03.019ICD10CMCellulitis of unspecified finger
L03.03ICD10CMCellulitis of toe
L03.031ICD10CMCellulitis of right toe
L03.032ICD10CMCellulitis of left toe
L03.039ICD10CMCellulitis of unspecified toe
L03.11ICD10CMCellulitis of other parts of limb
L03.111ICD10CMCellulitis of right axilla
L03.112ICD10CMCellulitis of left axilla
L03.113ICD10CMCellulitis of right upper limb
L03.114ICD10CMCellulitis of left upper limb
L03.115ICD10CMCellulitis of right lower limb
L03.116ICD10CMCellulitis of left lower limb
L03.119ICD10CMCellulitis of unspecified part of limb
L03.211ICD10CMCellulitis of face
L03.213ICD10CMPeriorbital cellulitis
L03.221ICD10CMCellulitis of neck
L03.222ICD10CMAcute lymphangitis of neck
L03.31ICD10CMCellulitis of trunk
L03.311ICD10CMCellulitis of abdominal wall
L03.312ICD10CMCellulitis of back [any part except buttock and flank]
L03.313ICD10CMCellulitis of chest wall
L03.314ICD10CMCellulitis of groin
L03.315ICD10CMCellulitis of perineum
L03.316ICD10CMCellulitis of umbilicus
L03.317ICD10CMCellulitis of buttock
L03.319ICD10CMCellulitis of trunk, unspecified
L03.31AICD10CMCellulitis of flank
L03.32AICD10CMAcute lymphangitis of flank
L03.81ICD10CMCellulitis of other sites
L03.811ICD10CMCellulitis of head [any part, except face]
L03.818ICD10CMCellulitis of other sites
L03.90ICD10CMCellulitis, unspecified
L08.9ICD10CMLocal infection of the skin and subcutaneous tissue, unspecified
N48.22ICD10CMCellulitis of corpus cavernosum and penis
Folliculitis
L73.9ICD10CMFollicular disorder, unspecified
Furunculosis
J34.0ICD10CMAbscess, furuncle and carbuncle of nose
L02.02ICD10CMFuruncle of face
L02.03ICD10CMCarbuncle of face
L02.12ICD10CMFuruncle of neck
L02.13ICD10CMCarbuncle of neck
L02.22ICD10CMFuruncle of trunk
L02.221ICD10CMFuruncle of abdominal wall
L02.222ICD10CMFuruncle of back [any part, except buttock and flank]
L02.223ICD10CMFuruncle of chest wall
L02.224ICD10CMFuruncle of groin
L02.225ICD10CMFuruncle of perineum
L02.226ICD10CMFuruncle of umbilicus
L02.227ICD10CMFuruncle of flank
L02.229ICD10CMFuruncle of trunk, unspecified
L02.23ICD10CMCarbuncle of trunk
L02.231ICD10CMCarbuncle of abdominal wall
L02.232ICD10CMCarbuncle of back [any part, except buttock and flank]
L02.233ICD10CMCarbuncle of chest wall
L02.234ICD10CMCarbuncle of groin
L02.235ICD10CMCarbuncle of perineum
L02.236ICD10CMCarbuncle of umbilicus
L02.237ICD10CMCarbuncle of flank
L02.239ICD10CMCarbuncle of trunk, unspecified
L02.32ICD10CMFuruncle of buttock
L02.33ICD10CMCarbuncle of buttock
L02.42ICD10CMFuruncle of limb
L02.421ICD10CMFuruncle of right axilla
L02.422ICD10CMFuruncle of left axilla
L02.423ICD10CMFuruncle of right upper limb
L02.424ICD10CMFuruncle of left upper limb
L02.425ICD10CMFuruncle of right lower limb
L02.426ICD10CMFuruncle of left lower limb
L02.429ICD10CMFuruncle of limb, unspecified
L02.43ICD10CMCarbuncle of limb
L02.431ICD10CMCarbuncle of right axilla
L02.432ICD10CMCarbuncle of left axilla
L02.433ICD10CMCarbuncle of right upper limb
L02.434ICD10CMCarbuncle of left upper limb
L02.435ICD10CMCarbuncle of right lower limb
L02.436ICD10CMCarbuncle of left lower limb
L02.439ICD10CMCarbuncle of limb, unspecified
L02.52ICD10CMFuruncle hand
L02.521ICD10CMFuruncle right hand
L02.522ICD10CMFuruncle left hand
L02.529ICD10CMFuruncle unspecified hand
L02.53ICD10CMCarbuncle of hand
L02.531ICD10CMCarbuncle of right hand
L02.532ICD10CMCarbuncle of left hand
L02.539ICD10CMCarbuncle of unspecified hand
L02.62ICD10CMFuruncle of foot
L02.621ICD10CMFuruncle of right foot
L02.622ICD10CMFuruncle of left foot
L02.629ICD10CMFuruncle of unspecified foot
L02.63ICD10CMCarbuncle of foot
L02.631ICD10CMCarbuncle of right foot
L02.632ICD10CMCarbuncle of left foot
L02.639ICD10CMCarbuncle of unspecified foot
L02.82ICD10CMFuruncle of other sites
L02.821ICD10CMFuruncle of head [any part, except face]
L02.828ICD10CMFuruncle of other sites
L02.83ICD10CMCarbuncle of other sites
L02.831ICD10CMCarbuncle of head [any part, except face]
L02.838ICD10CMCarbuncle of other sites
L02.92ICD10CMFuruncle, unspecified
L02.93ICD10CMCarbuncle, unspecified
Paronychia
L03.01ICD10CMCellulitis of finger
L03.011ICD10CMCellulitis of right finger
L03.012ICD10CMCellulitis of left finger
L03.019ICD10CMCellulitis of unspecified finger
L03.03ICD10CMCellulitis of toe
L03.031ICD10CMCellulitis of right toe
L03.032ICD10CMCellulitis of left toe
L03.039ICD10CMCellulitis of unspecified toe
L03.90ICD10CMCellulitis, unspecified

ICD code information from First Databank (FDB).

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data