Rheumatrex (methotrexate sodium)
Last reviewed · Source: First Databank (FDB) drug data
Overview
USES: Methotrexate is used to treat certain types of cancer (such as acute lymphoblastic leukemia, non-Hodgkin's lymphoma), severe psoriasis that has not responded to other treatments, or rheumatoid arthritis. It may also be used to treat a certain type of arthritis in children (polyarticular juvenile idiopathic arthritis - pJIA). Methotrexate belongs to a class of drugs known as antimetabolites.
It works by slowing or stopping the growth of cancer cells and blocking the immune system from attacking healthy tissue. Early treatment of rheumatoid arthritis with methotrexate helps to reduce further joint damage and to preserve joint function.
Generic name: methotrexate sodium
Pronunciation: (METH-oh-TREX-ate)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
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Indications
The following indications are listed for Rheumatrex:
- Acute Lymphoid Leukemia
- Burkitt's Lymphoma
- Carcinoma Of Breast
- Gestational Trophoblastic Neoplasia
- Mycosis Fungoides
- Non-Hodgkin's Lymphoma
- Polyarticular Juvenile Idiopathic Arthritis
- Rheumatoid Arthritis
- Severe Recalcitrant Psoriasis
- Squamous Cell Carcinoma Of Head And Neck
Also known as: Acute Lymphatic Leukemia, Acute Lymphocytic Leukemia, Acute Lymphogenous Leukemia, Arthritis Deformans, Arthrosis Deformans, Breast Carcinoma, Burkitt's Tumor, Epidermoid Carcinoma Of The Head And Neck, Lymphoblastic Leukemia, Nodose Rheumatism, Non-Hodgkin's Type Lymphoma, Polyarticular Jia, Polyarticular Jra, Polyarticular Juvenile Chronic Arthritis, Polyarticular Juvenile Rheumatoid Arthritis, Rheumatic Arthritis, Rheumatic Gout, Severe Intractable Psoriasis, Severe Refractory Psoriasis, Trophoblastic Neoplasm.
Dosing
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Drug interactions
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There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
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There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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ICD codes
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Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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