Sulfadiazine (sulfadiazine)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Sulfadiazine is an intermediate-acting antibacterial sulfonamide.
Sulfadiazine shares the actions and uses of the other anti-infective sulfonamides.
Generic name: sulfadiazine
Pronunciation: (sull-fuh-DYE-uh-zeen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Sulfadiazine
Indications
The following indications are listed for Sulfadiazine:
- Acquired Immunodeficiency Syndrome With Toxoplasmosis
- Bacterial Urinary Tract Infection
- Congenital Toxoplasmosis
- Encephalitis Due To Toxoplasmosis
- Nocardiosis
- Rheumatic Fever Prevention
- Toxoplasmosis
Also known as: Encephalitis Due To Toxoplasma Gondii, Nocardiosis Infections, Rheumatic Fever Prophylaxis.
Dosing
The usual adult dosage of sulfadiazine is 2-4 g initially, followed by 2-4 g daily administered in 3-6 equally divided doses.
When sulfadiazine is used in infants and children older than 2 months of age, the manufacturer recommends 75 mg/kg or 2 g/m2 initially, followed by 150 mg/kg or 4 g/m2 daily administered in 4-6 equally divided doses. For the treatment of mild, moderate, or severe infections, the American Academy of Pediatrics (AAP) recommends that children beyond the neonatal period receive a sulfadiazine dosage of 120-150 mg/kg daily given in 4-6 divided doses. Pediatric dosage should not exceed 6 g daily.
Sulfadiazine is administered orally.
Patients should be instructed to drink one full glass (250 mL) of water with each dose of sulfadiazine and at frequent intervals throughout the day while they are receiving the drug.
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Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
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There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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