Ecoza (econazole nitrate)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Econazole, an imidazole derivative, is a synthetic azole antifungal agent.
USES: Econazole foam is used to treat athlete's foot. Econazole is an azole antifungal that works by preventing the growth of fungus.
Generic name: econazole nitrate
Pronunciation: (e-KON-a-zole)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Ecoza
Indications
The following indications are listed for Ecoza:
- Tinea Pedis
Also known as: Dermatomycosis Pedis, Tinea Of The Foot.
Dosing
No dosing information is available for this tab.
Econazole nitrate is applied topically to the skin as a 1% cream.
The cream should not be applied to the eye and should not be administered intravaginally.
A sufficient amount of the cream should be applied to cover the affected areas of skin and rubbed in gently.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
Reproduction studies in mice, rabbits, and rats using orally administered econazole nitrate have not revealed evidence of teratogenicity; however, gestation has been reported to be prolonged in rats following oral administration of the drug. Prolonged gestation has not been reported following intravaginal administration of econazole nitrate in humans. Fetotoxic or embryotoxic effects were observed in reproduction studies in rats receiving oral econazole nitrate dosages 10-40 times the topical human dosage, and similar effects occurred in mice, rabbits, and/or rats receiving oral dosages 40 or 80 times the topical human dosage. Econazole nitrate 1% cream should be used during the first trimester of pregnancy only when considered essential to the welfare of the patient and during the second or third trimester of pregnancy only when clearly needed.
Following oral administration of econazole nitrate to lactating rats, econazole and/or its metabolites are distributed into milk and have been detected in nursing pups. In addition, in lactating rats receiving oral econazole nitrate dosages 40 or 80 times the topical human dosage, postpartum viability of pups and survival to weaning were reduced; however, at these dosages, maternal toxicity was present and may have been a contributing factor. Since it is not known whether econazole nitrate is distributed into human milk following topical application, econazole nitrate 1% cream should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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