Bacitracin-Polymyxin B (bacitracin/polymyxin B sulfate)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Bacitracin is a polypeptide antibiotic.
Polymyxin B is a polymyxin antibiotic.
USES: This medication is used to treat eye infections. This product contains bacitracin and polymyxin, antibiotics that work by stopping the growth of bacteria. This medication treats only bacterial eye infections.
It will not work for other types of eye infections. Using any antibiotic when it is not needed can cause it to not work for future infections.
Generic name: bacitracin/polymyxin B sulfate
Pronunciation: (BAS-i-TRAY-sin/POL-ee-MIX-in)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Bacitracin-Polymyxin B
Indications
The following indications are listed for Bacitracin-Polymyxin B:
- Superficial Ocular Infection
Also known as: Superficial Ophthalmic Infection.
Dosing
Dosage of bacitracin or bacitracin zinc is expressed in terms of the base.
Potency and dosage of polymyxin B sulfate are expressed in terms of polymyxin B activity (units of polymyxin B).
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies have not been performed with bacitracin. It is not known whether ophthalmic preparations containing bacitracin or bacitracin zinc can cause fetal harm when administered to pregnant women.
Fixed-combination ophthalmic preparations containing bacitracin zinc and polymyxin B sulfate with or without neomycin sulfate should be used during pregnancy only if clearly needed.
Fixed-combination ophthalmic preparations containing bacitracin zinc, neomycin sulfate, polymyxin B sulfate, and a corticosteroid (i.e., hydrocortisone, hydrocortisone acetate) should be used during pregnancy only if potential benefits justify potential risks to the fetus.
Animal reproduction studies have not been performed with polymyxin B sulfate. It is not known whether ophthalmic preparations containing polymyxin B sulfate can cause fetal harm when administered to pregnant women.
Fixed-combination ophthalmic preparations of polymyxin B sulfate and bacitracin zinc or polymyxin B sulfate, neomycin sulfate, and either bacitracin zinc or gramicidin should be used during pregnancy only if clearly needed.
Because trimethoprim may interfere with folic acid metabolism, fixed-combination ophthalmic preparations containing polymyxin B sulfate and trimethoprim sulfate should be used during pregnancy only if potential benefits justify potential risks to the fetus.
Fixed-combination ophthalmic preparations containing polymyxin B sulfate, other anti-infectives (i.e., neomycin sulfate, bacitracin zinc), and a corticosteroid (i.e., dexamethasone, hydrocortisone, hydrocortisone acetate) should be used during pregnancy only if potential benefits justify potential risks to the fetus.
Fixed-combination otic preparations containing polymyxin B sulfate, neomycin sulfate, and hydrocortisone should be used during pregnancy only if potential benefits justify potential risks to the fetus.
It is not know whether bacitracin is distributed into milk.
Bacitracin and fixed-combination ophthalmic preparations containing bacitracin zinc and polymyxin B sulfate with or without neomycin sulfate should be used with caution in nursing women.
The manufacturers of fixed-combination ophthalmic preparations containing bacitracin zinc, neomycin sulfate, polymyxin B sulfate, and a corticosteroid (i.e., hydrocortisone, hydrocortisone acetate) state that a decision should be made whether to discontinue nursing or the ophthalmic preparation, taking into account the importance of the drug to the woman.
Some experts consider topical bacitracin compatible with nursing.
Fixed-combination ophthalmic preparations containing polymyxin B sulfate and other anti-infectives (i.e., bacitracin zinc, gramicidin, neomycin sulfate, trimethoprim sulfate) should be used with caution in nursing women.
Fixed-combination ophthalmic preparations containing polymyxin B sulfate, neomycin sulfate, and dexamethasone should be used with caution in nursing women.
The manufacturers of fixed-combination ophthalmic preparations containing polymyxin B sulfate, neomycin sulfate, bacitracin zinc, and hydrocortisone or hydrocortisone acetate state that a decision should be made whether to discontinue nursing or the ophthalmic preparation, taking into account the importance of the drug to the woman.
Fixed-combination otic preparations containing polymyxin B sulfate, neomycin sulfate, and hydrocortisone should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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