Synvisc (hylan G-F 20)
Visco-Elastics, Intra-articular Intraarticular Syringe (Ml)
Last reviewed · Source: First Databank (FDB) drug data
Overview
USES: This medication is used to treat knee pain in patients with joint inflammation (osteoarthritis). It is usually used in patients who have not responded to other treatments such as acetaminophen, exercise, or physical therapy. Hyaluronate (also known as hyaluronan) is similar to a substance that occurs naturally in the joints.
It may work by acting as a lubricant and shock absorber in the joint, helping the knee to move smoothly, thereby lessening pain.
Generic name: hylan G-F 20
Pronunciation: (HYE-al-ure-ON-ate)
Drug class: Visco-Elastics, Intra-articular
Therapeutic class: Locomotor System
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Synvisc
Indications
The following indications are listed for Synvisc:
- Osteoarthritis Of The Knee
Also known as: Degenerative Arthritis Of The Knee, Degenerative Joint Disease Of The Knee, Djd Of The Knee, Hypertrophic Arthritis Of The Knee, Oa Of The Knee, Osteoarthrosis Of The Knee.
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Synvisc Syringe | Maintenance | Inject 2 milliliters (16 mg) by intra-articular route once weekly into the affected knee. |
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Infection of bone, joint, skin, or soft tissue of knee
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Dyspnea
- Infectious disorder of joint
- Thrombocytopenic disorder
- Urticaria
More Frequent
- Injection site sequelae
- Knee inflammation
Rare or Very Rare
- Chills
- Cramps in legs
- Dizziness
- Fatigue
- Fever
- Flushing
- Headache disorder
- Lip hypertrophy
- Malaise
- Myalgia
- Nausea
- Pain
- Paresthesia
- Peripheral edema
- Pruritus of skin
- Skin rash
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Osteoarthritis of the knee | ||
| M17 | ICD10CM | Osteoarthritis of knee |
| M17.0 | ICD10CM | Bilateral primary osteoarthritis of knee |
| M17.1 | ICD10CM | Unilateral primary osteoarthritis of knee |
| M17.10 | ICD10CM | Unilateral primary osteoarthritis, unspecified knee |
| M17.11 | ICD10CM | Unilateral primary osteoarthritis, right knee |
| M17.12 | ICD10CM | Unilateral primary osteoarthritis, left knee |
| M17.2 | ICD10CM | Bilateral post-traumatic osteoarthritis of knee |
| M17.3 | ICD10CM | Unilateral post-traumatic osteoarthritis of knee |
| M17.30 | ICD10CM | Unilateral post-traumatic osteoarthritis, unspecified knee |
| M17.31 | ICD10CM | Unilateral post-traumatic osteoarthritis, right knee |
| M17.32 | ICD10CM | Unilateral post-traumatic osteoarthritis, left knee |
| M17.4 | ICD10CM | Other bilateral secondary osteoarthritis of knee |
| M17.5 | ICD10CM | Other unilateral secondary osteoarthritis of knee |
| M17.9 | ICD10CM | Osteoarthritis of knee, unspecified |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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