Giltuss Severe Sinus (oxymetazoline HCl)
Nasal Decongestants Nasal Aerosol, Mist
Last reviewed · Source: First Databank (FDB) drug data
Overview
Oxymetazoline hydrochloride, an imidazoline-derivative sympathomimetic amine, is a vasoconstrictor.
USES: This medication is used for temporary relief of congestion in the nose caused by various conditions including the common cold, sinusitis, hay fever, and allergies. It works by narrowing the blood vessels in the nose area, reducing swelling and congestion.
Generic name: oxymetazoline HCl
Drug class: Nasal Decongestants
Therapeutic class: Respiratory Therapy Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Giltuss Severe Sinus
Indications
The following indications are listed for Giltuss Severe Sinus:
- Nasal Congestion
Also known as: Nasal Stuffiness.
Dosing
No dosing information is available for this tab.
Oxymetazoline hydrochloride nasal solutions are applied topically to the nasal mucosa as sprays. Oxymetazoline hydrochloride nasal solutions also are administered by a nasal pump that produces metered sprays. Ophthalmic solutions of the drug are applied topically to the conjunctiva. Care must be taken to avoid contamination of the dropper, inhaler, or spray dispenser. It is recommended that contact lenses be removed before topical administration of the ophthalmic solution.
Sprays (including metered sprays) should be delivered or pumped into each nostril with the patient's head erect so that excess solution is not released. Prior to initial use of metered sprays, the nasal inhalers should be primed by depressing the pump firmly several times. To minimize the risk of spreading infections, droppers, inhalers, and spray dispensers should not be used by more than one person, and tips of the dispensers, inhalers, or droppers should be rinsed with hot water or wiped clean following use.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
Moderate Interaction: Assess the risk to the patient and take action as needed.
Intranasal Decongestants/Zavegepant
SEVERITY LEVEL: 3-Moderate Interaction: Assess the risk to the patient and take action as needed.
MECHANISM OF ACTION: Intranasal decongestants may decrease the absorption of zavegepant.(1)
CLINICAL EFFECTS: Concurrent administration of intranasal decongestants may result in decreased systemic exposure and effectiveness of zavegepant.(1)
PREDISPOSING FACTORS: None determined.
PATIENT MANAGEMENT: Avoid concurrent use of intranasal decongestants with zavegepant. If concurrent use is unavoidable, use the decongestant at least 1 hour after zavegepant.(1)
DISCUSSION: Intranasal decongestants may lower absorption of zavegepant. This effect has not been clinically evaluated.(1)
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
- Angle-closure glaucoma
- Benign prostatic hyperplasia
- Atherosclerotic cardiovascular disease
- Coronary artery disease
- Diabetes mellitus
- Hypertension
- Hyperthyroidism
Adverse reactions
There is no enhanced messaging for this drug.
Less Frequent
- Dizziness
- Headache disorder
- Insomnia
- Nervousness
- Rebound nasal congestion
- Tremor
Rare or Very Rare
- Cardiac arrhythmia
- Hypertension
Less Frequent
- Dry nose
- Nasal passage irritation
- Rhinorrhea
- Sneezing
Rare or Very Rare
- Nausea
- Palpitations
Precautions
No enhanced messaging available.
No enhanced messaging available.
Safe use of oxymetazoline during pregnancy has not been established. Oxymetazoline hydrochloride ophthalmic or nasal solutions should be used during pregnancy only when instructed by a clinician.
It is not known whether oxymetazoline is distributed into milk. Topical oxymetazoline preparations should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Nasal congestion | ||
| R09.81 | ICD10CM | Nasal congestion |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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