Prazosin Hcl (prazosin HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Prazosin hydrochloride is an alpha1-adrenergic blocking agent.
USES: This medication is used to treat high blood pressure. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. Prazosin belongs to a class of drugs known as alpha blockers.
It works by relaxing blood vessels so blood can flow more easily.
Generic name: prazosin HCl
Pronunciation: (PRAY-zoe-sin)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Prazosin Hcl
Indications
The following indications are listed for Prazosin Hcl:
- Hypertension
Also known as: Elevated Blood Pressure, Essential Hypertension, Hyperpiesia, Hyperpiesis, Hypertensive Disorder, Systemic Arterial Hypertension.
Dosing
Dosage of prazosin hydrochloride is expressed in terms of prazosin and must be adjusted according to the patient's blood pressure response and tolerance.
For the management of hypertension in adults with renal failure, therapy with prazosin should be initiated with 1 mg twice daily. Patients with chronic renal failure may require only small doses of the drug.
Prazosin hydrochloride is administered orally.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
Prazosin hydrochloride has been associated with decreased litter size at birth and at 1, 4, and 21 days of age in rats receiving more than 225 times the usual maximum recommended human dosage; no evidence of drug-related external, visceral, or skeletal fetal abnormalities was observed. No prazosin-related external, visceral, or skeletal abnormalities were observed in the offspring of pregnant rabbits and monkeys receiving dosages more than 225 and 12 times the usual maximum recommended human dosage, respectively. Prazosin has been used alone or in combination with other hypotensive agents for the management of severe hypertension in a limited number of pregnant women without apparent adverse effect on the fetus. There are no adequate and well-controlled studies to date using prazosin in pregnant women, however, and the drug should be used during pregnancy only when the potential benefits justify the possible risks to the fetus.
Since prazosin is distributed into milk in small amounts, the drug should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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