Lmd In Nacl (dextran 40 in 0.9 % sodium chloride)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Dextran 40, a nonprotein colloid, is a plasma volume expander.
Dextran 40 is a nonprotein colloid used for early fluid replacement and for plasma volume expansion in the adjunctive treatment of certain types of shock or impending shock when whole blood or blood products are not available, or when the need for haste precludes the necessary cross-matching of blood. Dextran 40 differs from dextran 70 and 75 in molecular weight and adverse effects. In addition to producing plasma volume expansion, dextran 40 appears to minimize sludging of blood as a result of its effects on microcirculation.
Types of shock for which dextran 40 may be used include those resulting from burns, surgery, hemorrhage, or other trauma in which a circulating volume deficit is present. Dextran 40 does not replace other forms of therapy but is complementary to fluids and electrolytes. For additional information, see Uses in Albumin Human 16:00.
Generic name: dextran 40 in 0.9 % sodium chloride
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
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Indications
The following indications are listed for Lmd In Nacl:
- Deep Vein Thrombosis Prevention
Also known as: Deep Vein Thrombosis Prophylaxis, Dvt Prevention.
Dosing
No dosing information is available for this tab.
Dextran 40 is administered in 10% solution by IV infusion. Because dextran 40 injections do not contain preservatives, partially used containers should be discarded.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
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There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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No enhanced messaging available.
Animal reproduction studies have not been performed with dextran 40; and it is also not known whether the drug can cause fetal harm when administered to pregnant women. Dextran 40 should be used during pregnancy only when clearly needed.
It is not known whether dextran 40 is excreted in human milk. Because of the potential for serious adverse reactions to dextran 40 in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the woman.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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