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Nitroglycerin In D5w (nitroglycerin in 5 % dextrose in water)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Nitroglycerin, an organic nitrate, is a vasodilating agent.

Generic name: nitroglycerin in 5 % dextrose in water

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

Today’s intelligence on Nitroglycerin In D5w

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Indications

The following indications are listed for Nitroglycerin In D5w:

  • Induction Of Intraoperative Hypotension
  • Left Ventricular Dysfunction Following Myocardial Infarction
  • Perioperative Hypertension
  • Unstable Angina Pectoris

Also known as: Crescendo Angina, Left Ventricular Dysfunction Following Acute Mi, Left Ventricular Dysfunction Following Acute Myocardial Infarction, Left Ventricular Dysfunction Following Ami, Left Ventricular Dysfunction Following Cardiac Infarct, Left Ventricular Dysfunction Following Cardiac Infarction, Left Ventricular Dysfunction Following Myocardial Infarct, Lv Dysfunction Following Mi, Preinfarction Syndrome, Unstable Angina.

Dosing

Dosage of nitroglycerin must be carefully adjusted according to the patient's requirements and response and the smallest effective dosage should be used. When nitroglycerin is administered IV, the type of IV administration set used, polyvinyl chloride (PVC) or non-PVC, must be considered in dosage estimations. It should be noted that dosages commonly used in early published studies were based on the use of PVC administration sets and are too high when non-PVC administration sets are used.

Continuous monitoring of blood pressure and heart rate, as well as other appropriate parameters (e.g., pulmonary capillary wedge pressure), must be performed in all patients. Adequate systemic blood pressure and coronary perfusion pressure must be maintained. Some patients with normal or low left ventricular filling pressures or pulmonary capillary wedge pressure may be extremely sensitive to the effects of IV nitroglycerin and may respond fully to dosages as low as 5 mcg/minute; these patients require particularly careful monitoring and dosage titration.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

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Adverse reactions

There is no enhanced messaging for this drug.

Precautions

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ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data