Griseofulvin Ultramicrosize (griseofulvin ultramicrosize)

Dosage of griseofulvin varies depending on whether the drug is administered as griseofulvin microsize or griseofulvin ultramicrosize. In addition, dosage recommendations for ultramicrosize griseofulvin vary slightly depending on the manufacturer and the particular formulation of the drug.

Dosage and duration of griseofulvin therapy should be individualized according to the requirements and response of the patient. Griseofulvin therapy generally needs to be continued for at least 4-12 weeks for the treatment of tinea capitis; at least 2-4 weeks for the treatment of tinea corporis; at least 4-8 weeks for tinea pedis; and from 4-6 months to a year or longer for tinea unguium.

Griseofulvin is administered orally as a single daily dose or in 2-4 equally divided doses.

No dosing information is available for this tab.

No dosing information is available for this tab.

There is no enhanced messaging for this drug.

There are no contraindication interactions for this drug.

There are no severe interactions for this drug.

There are no moderate interactions for this drug.

There is no enhanced messaging for this drug.

There are no contraindication contraindications for this drug.

There are no severe contraindications for this drug.

There are no moderate contraindications for this drug.

There is no enhanced messaging for this drug.

There are no severe adverse reactions for this drug.

There are no less severe adverse reactions for this drug.

No enhanced messaging available.

No enhanced messaging available.

Griseofulvin may cause fetal toxicity when administered to pregnant women. Griseofulvin is embryotoxic and/or teratogenic in animals. Fetal abnormalities have included multiple defects in rats; cleft palate in dogs; cleft palate and cardiac, CNS, and ocular defects in cats; and skeletal defects in mice. Although the potential risk to the fetus of maternal use of griseofulvin remains to be clearly established in humans, at least two women who received griseofulvin therapy during the first trimester of pregnancy delivered conjoined twins, and some women who received the drug during pregnancy reportedly have had spontaneous abortions or delivered infants with other congenital malformations. In an analysis of spontaneous or threatened abortion diagnoses in one large group of women, the estimated relative risk of spontaneous abortion in women who received griseofulvin within the 3 months prior to such diagnoses was estimated to be increased 2.5 times. Some experts state that while limited data indicate that the outcome for most pregnancies is likely to be normal after fetal exposure to the drug, evidence from the US Food and Drug Administration's teratogen information system indicates that an association between conjoined twins and griseofulvin use exists and data are insufficient to exclude a moderate association between use of the drug and other defects. However, other experts have questioned whether an association between use of the drug and conjoined twinning has been established. The manufacturers state that griseofulvin is contraindicated in women who are or may become pregnant. One manufacturer states that additional contraceptive precautions should be taken during and for 1 month after griseofulvin therapy and that griseofulvin should not be used in any woman who intends to become pregnant within 1 month after therapy with the drug would be discontinued. If griseofulvin is inadvertently administered during pregnancy or if the patient becomes pregnant while receiving the drug, the patient should be informed of the potential hazard to the fetus.

No enhanced messaging available.

No enhanced messaging available.