Prednisolone Acetate (prednisolone acetate/PF)

Potency of some sodium phosphate preparations is expressed in terms of prednisolone phosphate.

For use in the eye, 1 or 2 drops of prednisolone acetate ophthalmic suspension or prednisolone sodium phosphate ophthalmic solution may be instilled into the conjunctival sac every hour during the day and every 2 hours during the night for initial therapy in severe cases. In mild or moderate inflammation or when a favorable response is attained in severe cases, dosage may be reduced to 1 or 2 drops every 3-12 hours.

Alternatively, prednisolone sodium phosphate ophthalmic ointment may be instilled into the conjunctival sac 3 or 4 times daily initially, and once or twice daily thereafter. The ointment also may be used at night in conjunction with daytime use of a suspension or solution to reduce the frequent applications required with the liquid dosage forms.

The lowest effective concentration should be used and, if improvement does not occur within several days, the drug should be discontinued and other therapy begun. The duration of treatment depends on the type and severity of the disease and may range from a few days to several weeks; long-term therapy should be avoided. When the drug is discontinued, dosage should be gradually tapered to avoid exacerbation of the disease.

Prednisolone acetate or sodium phosphate is applied topically to the eye. Care should be taken to avoid contamination of the tip of the ointment tube or dropper when the drug is used ophthalmically.

No dosing information is available for this tab.

No dosing information is available for this tab.

There is no enhanced messaging for this drug.

There are no contraindication interactions for this drug.

There are no severe interactions for this drug.

There are no moderate interactions for this drug.

There is no enhanced messaging for this drug.

• Fungal infection of eye
• Herpes simplex dendritic keratitis
• Tuberculosis of the eye
• Vaccinia virus keratitis

• Amebic infection of the eye
• Ocular hypertension

• Corneal erosion
• Diabetes mellitus
• Krukenberg spindle
• Open angle glaucoma
• Severe myopia

There is no enhanced messaging for this drug.

Less Frequent

• Ocular hypertension

Rare or Very Rare

• Adrenocortical insufficiency
• Cataracts
• Central serous chorioretinopathy
• Corneal degeneration
• Corneal edema
• Corneal erosion
• Corneal ulcer
• Fungal infection of eye
• Glaucoma
• Globe perforation
• Hypercortisolism
• Hypersensitivity drug reaction
• Keratitis
• Optic nerve damage
• Punctate keratitis
• Reduced visual acuity
• Uveitis
• Visual changes
• Visual field defect

More Frequent

• Blurred vision

Less Frequent

• Headache disorder
• Iritis
• Ocular pain

Rare or Very Rare

• Accommodation disorder
• Allergic dermatitis
• Blepharoptosis
• Calcification of cornea
• Chemosis
• Conjunctival hyperemia
• Conjunctivitis
• Dizziness
• Dysgeusia
• Eye tearing
• Foreign body sensation of eye
• Impaired wound healing
• Mydriasis
• Ocular infection
• Ocular irritation
• Ocular itching
• Ocular redness
• Photophobia
• Urticaria

No enhanced messaging available.

No enhanced messaging available.

No enhanced messaging available.

No enhanced messaging available.

No enhanced messaging available.