Dantrium (dantrolene sodium)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Dantrolene sodium is a direct-acting skeletal muscle relaxant.
Generic name: dantrolene sodium
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Dantrium
Indications
The following indications are listed for Dantrium:
- Malignant Hyperthermia
- Malignant Hyperthermia Prevention
Also known as: Malignant Hyperthermia Prophylaxis.
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
There are no adequate and well-controlled studies of dantrolene in pregnant women. The drug has been shown to be embryocidal in rabbits and to decrease pup survival in rats when given at doses 7 times the human oral dose. Dantrolene sodium readily crosses the placenta but, when given to pregnant women at term in a dosage of 100 mg daily, no adverse respiratory or neuromuscular effects were detected at low dose in neonates born to these women. Further studies are needed, particularly with higher dosages. Dantrolene should not be used in women who are or may become pregnant unless the possible benefits outweigh the potential risks to the fetus.
Dantrolene is distributed into human milk. Because of the potential for serious adverse effects in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the woman.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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