Exoderm (sodium thiosulfate/salicylic acid)
Topical Antifungals Topical Lotion (Ml)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Sodium thiosulfate is used as an antifungal agent.
Sodium thiosulfate is used topically in the treatment of tinea versicolor. Sodium thiosulfate also is used systemically (as an injection) as an adjunct in the management of cyanide poisoning (specialized references or the manufacturers' labeling should be consulted) and to reduce the risk of nephrotoxicity associated with cisplatin therapy (see Cisplatin 10:00).
Generic name: sodium thiosulfate/salicylic acid
Drug class: Topical Antifungals
Therapeutic class: Dermatological
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Exoderm
Indications
No indications are available for this drug.
Dosing
Sodium thiosulfate is applied topically in the form of a 25% lotion or solution (no longer commercially available in the US). A commercially available lotion also containing salicylic acid may be used. Alternatively, aqueous solutions of the drug are prepared extemporaneously.
For the treatment of tinea versicolor, a thin film of sodium thiosulfate 25% lotion or solution is applied to the involved areas twice daily; these areas should be thoroughly cleansed and dried before applying the lotion or solution. Although evidence of active infection may disappear within a few days, treatment is usually continued for several weeks to months.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Aspirin exacerbated respiratory disease
- Hemolytic anemia from pyruvate kinase and g6PD deficiencies
There are no severe contraindications for this drug.
- Peripheral vascular disease
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Anaphylaxis
- Burns
- Dyspnea
- Facial edema
- Hypersensitivity drug reaction
- Periorbital edema
- Pharyngeal edema
- Skin ulcer
- Superficial skin ulcer
- Syncope
- Throat constriction
- Urticaria
More Frequent
- Stinging of skin
Less Frequent
- Dry skin
- Skin irritation
Rare or Very Rare
- Pruritus of skin
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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