Nystatin (nystatin)
Mouth and Throat Antifungal Agents Oral Tablet; Topical Cream (Gram); Topical Ointment (Gram); Topical Powder (Gram)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Nystatin, a polyene antibiotic, is an antifungal agent.
USES: Nystatin is used to treat fungal skin infections. Nystatin is an antifungal that works by stopping the growth of fungus.
Generic name: nystatin
Pronunciation: (NYE-stat-in)
Drug class: Mouth and Throat Antifungal Agents
Therapeutic class: Anti-Infective Agents
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Nystatin
Indications
The following indications are listed for Nystatin:
- Cutaneous Candidiasis
Also known as: Cutaneous Candidosis, Cutaneous Moniliasis.
Dosing
Dosage of nystatin is expressed in terms of USP nystatin units.
Nystatin is applied topically to the skin as a cream, ointment, or powder. Nystatin also is commercially available in fixed combination with a corticosteroid (i.e., triamcinolone acetonide) for topical application to the skin as a cream or ointment.
Nystatin is applied topically to the oral cavity as an oral suspension and is administered orally as film-coated tablets.
Although nystatin has been administered intravaginally, intravaginal preparations of the drug are no longer commercially available in the US.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Nystatin 100,000 Unit/Gm Cream | Maintenance | Apply to the affected area(s) by topical route 2 times per day. |
| Nystatin 100,000 Unit/Gm Powd | Maintenance | Apply to the affected area(s) by topical route 2 times per day. |
| Nystatin 100,000 Unit/Gm Oint | Maintenance | Apply to the affected area(s) by topical route 2 times per day. |
| Nystatin 500,000 Unit Oral Tab | Maintenance | Take 1 tablet (500,000 unit) by oral route 3 times per day continuingtreatment for at least 2 days after symptoms have disappeared. |
| Drug label | Dosing type | Instructions |
|---|---|---|
| Nystatin 500,000 Unit Oral Tab | Maintenance | Take 1 tablet (500,000 unit) by oral route 3 times per day continuingtreatment for at least 2 days after symptoms have disappeared. |
| Nystatin 100,000 Unit/Gm Oint | Maintenance | Apply to the affected area(s) by topical route 2 times per day. |
| Nystatin 100,000 Unit/Gm Cream | Maintenance | Apply to the affected area(s) by topical route 2 times per day. |
| Nystatin 100,000 Unit/Gm Powd | Maintenance | Apply to the affected area(s) by topical route 2 times per day. |
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
- No disease contraindications
Adverse reactions
There is no enhanced messaging for this drug.
Rare or Very Rare
- Bronchospastic pulmonary disease
- Stevens-johnson syndrome
- Tachycardia
- Urticaria
Less Frequent
- Abdominal pain with cramps
- Diarrhea
- Gastrointestinal irritation
- Nausea
- Vomiting
Rare or Very Rare
- Eczema
- Facial edema
- Myalgia
- Pruritus of skin
- Skin irritation
- Skin rash
- Skin rash
- Treatment site sequelae
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies have not been performed using topical or oral nystatin. It is not known whether nystatin can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity.
Topical nystatin should be used during pregnancy only if potential benefits outweigh potential risks to the fetus.
Oral nystatin (oral suspension, tablets) should be used during pregnancy only if clearly needed.
Fixed-combination topical preparations containing nystatin and triamcinolone acetonide should be used during pregnancy only if potential benefits outweigh potential risks to the fetus. Topical preparations containing corticosteroids should not be used extensively, in large amounts, or for prolonged periods during pregnancy.
It is not known whether nystatin is distributed into human milk.
Nystatin and fixed combinations containing nystatin and triamcinolone acetonide should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Cutaneous candidiasis | ||
| B37.2 | ICD10CM | Candidiasis of skin and nail |
| Gastrointestinal candidiasis | ||
| B37.82 | ICD10CM | Candidal enteritis |
| Mucocutaneous candidiasis | ||
| B37.0 | ICD10CM | Candidal stomatitis |
| B37.2 | ICD10CM | Candidiasis of skin and nail |
| B37.3 | ICD10CM | Candidiasis of vulva and vagina |
| B37.31 | ICD10CM | Acute candidiasis of vulva and vagina |
| B37.32 | ICD10CM | Chronic candidiasis of vulva and vagina |
| B37.42 | ICD10CM | Candidal balanitis |
| B37.83 | ICD10CM | Candidal cheilitis |
| Oral candidiasis | ||
| B37.0 | ICD10CM | Candidal stomatitis |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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