Thiola (tiopronin)
Urinary Stone Agents Oral Tablet
Last reviewed · Source: First Databank (FDB) drug data
Overview
USES: This medication is used to prevent kidney stones in people with a certain inherited disorder (cystinuria). Cystinuria occurs when there is too much of a certain natural substance (the amino acid cystine) in the urine, leading to formation of kidney stones. Tiopronin works by making cystine more dissolvable in the urine.
This medication should be used in combination with other methods to prevent kidney stones (such as drinking plenty of water, taking alkali treatment, following a special diet).
Generic name: tiopronin
Pronunciation: (tie-oh-PRO-nin)
Drug class: Urinary Stone Agents
Therapeutic class: Genitourinary Therapy
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Thiola
Indications
The following indications are listed for Thiola:
- Cystinuria
Dosing
No dosing information is available for this tab.
No dosing information is available for this tab.
| Drug label | Dosing type | Instructions |
|---|---|---|
| Thiola 100 Mg Tablet | Maintenance | Take 3 tablets (300 mg) by oral route 3 times per day. |
| Drug label | Dosing type | Instructions |
|---|---|---|
| Tiopronin 100 Mg Tablet | Maintenance | Take 3 tablets (300 mg) by oral route 3 times per day. |
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
- Lactation
- Proteinuria
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
More Frequent
- Allergic dermatitis
- Aphthous stomatitis
- Ecchymosis
- Elastosis perforans serpiginosa
- Jaundice
- Pemphigus
- Pruritus of skin
- Urticaria
Less Frequent
- Anemia
- Arthralgia
- Blood dyscrasias
- Chills
- Dyspnea
- Edema
- Eosinophilia
- Fever
- Hematuria
- Laryngeal edema
- Leukopenia
- Lymphadenopathy
- Myalgia
- Nephrotic syndrome
- Proteinuria
- Thrombocytopenic disorder
Rare or Very Rare
- Angioedema
- Bronchiolitis
- Chronic heart failure
- Goodpasture's syndrome
- Hemoptysis
- Pharyngitis
- Pulmonary infiltrates
- Renal failure
- Systemic lupus erythematosus
More Frequent
- Abnormal desquamation
- Anorexia
- Diarrhea
- Dry skin
- Fatigue
- Flatulence
- Nausea
- Skin atrophy
- Skin rash
- Vomiting
Less Frequent
- Dysgeusia
- General weakness
- Parosmia
Rare or Very Rare
- Abdominal distension
- Acute abdominal pain
- Cheilosis
- Chest pain
- Dyspepsia
- Headache disorder
- Hypoesthesia
- Loss of taste
- Neck pain
- Peripheral edema
- Vertigo
- Weight gain
- Xerostomia
Precautions
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
| Code | Type | Description |
|---|---|---|
| Cystinuria | ||
| E72.01 | ICD10CM | Cystinuria |
ICD code information from First Databank (FDB).
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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