Sulfadiazine (sulfadiazine)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Sulfadiazine is an intermediate-acting antibacterial sulfonamide.

Sulfadiazine shares the actions and uses of the other anti-infective sulfonamides.

Generic name: sulfadiazine
Pronunciation: (sull-fuh-DYE-uh-zeen)

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

Today’s intelligence on Sulfadiazine

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Indications

The following indications are listed for Sulfadiazine:

  • Acquired Immunodeficiency Syndrome With Toxoplasmosis
  • Bacterial Urinary Tract Infection
  • Congenital Toxoplasmosis
  • Encephalitis Due To Toxoplasmosis
  • Nocardiosis
  • Rheumatic Fever Prevention
  • Toxoplasmosis

Also known as: Encephalitis Due To Toxoplasma Gondii, Nocardiosis Infections, Rheumatic Fever Prophylaxis.

Dosing

The usual adult dosage of sulfadiazine is 2-4 g initially, followed by 2-4 g daily administered in 3-6 equally divided doses.

When sulfadiazine is used in infants and children older than 2 months of age, the manufacturer recommends 75 mg/kg or 2 g/m2 initially, followed by 150 mg/kg or 4 g/m2 daily administered in 4-6 equally divided doses. For the treatment of mild, moderate, or severe infections, the American Academy of Pediatrics (AAP) recommends that children beyond the neonatal period receive a sulfadiazine dosage of 120-150 mg/kg daily given in 4-6 divided doses. Pediatric dosage should not exceed 6 g daily.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

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Adverse reactions

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Precautions

No enhanced messaging available.

ICD codes

No ICD codes are available for this drug.

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data