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Antifungal (undecylenic acid)

Topical Antifungals Topical Aerosol, Powder (Gram); Topical Aerosol, Spray (Gram)

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Last reviewed · Source: First Databank (FDB) drug data

Overview

Undecylenic acid and undecylenate salts are antifungal agents.

Undecylenic acid and undecylenate salts (e.g., calcium undecylenate, copper undecylenate, zinc undecylenate) are topical antifungal agents. The drugs usually are used in combination, with the combined potency labeled in terms of total undecylenate, although they also can be used individually as antifungal agents. The combination containing zinc undecylenate and undecylenic acid is sometimes referred to as zincundecate.

The drugs are used topically in the treatment of athlete's foot (tinea pedis), jock itch (tinea cruris), and other skin infections caused by dermatophytic fungi (ringworm).

Generic name: undecylenic acid
Pronunciation: (un-de-sil-EN-ik)
Drug class: Topical Antifungals
Therapeutic class: Dermatological

Reference product & biosimilars

No reference, biosimilar or interchangeable associated with this drug.

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Indications

The following indications are listed for Antifungal:

  • Dermatophytosis
  • Tinea Corporis
  • Tinea Pedis

Also known as: Corporeal Ringworm, Dermatomycosis Pedis, Tinea, Tinea Circinata, Tinea Glabrosa, Tinea Infection, Tinea Of The Foot.

Dosing

Undecylenic acid and undecylenate salts are used individually or in combination in total concentrations of 10-25%. Preparations containing the drugs are applied topically twice daily after cleansing the affected area. The ointment should be used at night. Treatment should usually be continued for 4 weeks when treating athlete's foot or ringworm and for 2 weeks when treating jock itch. Preparations containing the drugs are not effective in the treatment of fungal infections of the scalp or nails.

The American Society of Health-System Pharmacists, Inc. represents that the information provided in the accompanying monograph was formulated with a reasonable standard of care, and in conformity with professional standards in the field. Readers are advised that decisions regarding use of drugs are complex medical decisions requiring the independent, informed decision of an appropriate health care professional, and that the information contained in the monograph is provided for informational purposes only. The manufacturer's labeling should be consulted for more detailed information. The American Society of Health-System Pharmacists, Inc. does not endorse or recommend the use of any drug. The information contained in the monograph is not a substitute for medical care.

Drug interactions

There is no enhanced messaging for this drug.

Contraindications

There is no enhanced messaging for this drug.

Adverse reactions

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Precautions

No enhanced messaging available.

ICD codes

CodeTypeDescription
Tinea barbae
B35.0ICD10CMTinea barbae and tinea capitis
Tinea capitis
B35.0ICD10CMTinea barbae and tinea capitis
Tinea corporis
B35.4ICD10CMTinea corporis
Tinea cruris
B35.6ICD10CMTinea cruris
Tinea manuum
B35.2ICD10CMTinea manuum
Tinea pedis
B35.3ICD10CMTinea pedis
Tinea versicolor
B36.0ICD10CMPityriasis versicolor

ICD code information from First Databank (FDB).

Formulary status

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Last reviewed · Source: First Databank (FDB) drug data