Ergomar (ergotamine tartrate)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Ergotamine is a naturally occurring ergot alkaloid.
USES: This medication is used to treat or prevent a certain type of headache (vascular headaches such as migraine headaches and cluster headaches). Ergotamine helps narrow widened blood vessels in the head, which reduces the throbbing effects of vascular headaches.
Generic name: ergotamine tartrate
Pronunciation: (er-GOT-a-meen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Ergomar
Indications
The following indications are listed for Ergomar:
- Cluster Headache Prevention
- Migraine
Also known as: Cluster Headache Prophylaxis.
Dosing
No dosing information is available for this tab.
Ergotamine tartrate is given sublingually. A combination of ergotamine tartrate and caffeine may be administered orally, or rectally as a suppository. If the suppositories become softened, they should be chilled in ice-cold water to solidify before removing the foil wrapper.
To be most effective, ergotamine tartrate should be administered as soon as possible after the first symptoms of a vascular headache (i.e., during the prodromal phase if there is one or at the beginning of an attack). The amount of drug required and the speed and degree of relief are thought to be directly related to the promptness with which the drug is started. After the initial dose is administered, the patient should lie down and relax in a quiet, darkened room. Ergotamine should not be administered within 24 hours of a selective serotonin agonist (e.g., sumatriptan). (See Drug Interactions: Selective Serotonin Agonists.)
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
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There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
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There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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Retarded fetal growth and increases in intrauterine death and resorption were reported in animals receiving ergotamine. It has been postulated that such fetotoxicity is associated with drug-induced increases in uterine motility and vasoconstriction in the placental vasculature. Ergotamine is contraindicated in women who are or may become pregnant.
Ergotamine is distributed into milk and may cause vomiting, diarrhea, weak pulse, unstable blood pressure, and seizures in nursing infants. Although ergot alkaloids have been reported to inhibit maternal pituitary prolactin secretion, decreased lactation has not been reported to date with ergotamine. Because of the potential for serious adverse reactions to ergotamine in nursing infants, a decision should be made whether to discontinue nursing or the drug, taking into account the importance of the drug to the woman.
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ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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