Demser (metyrosine)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Metyrosine is an inhibitor of catecholamine synthesis.
USES: This medication is used to treat high blood pressure in people with a certain adrenal gland tumor (pheochromocytoma). Metyrosine is used to prevent high blood pressure before and immediately after surgery to remove the tumor. It is also used long-term in people who cannot have the surgery.
It is not used for other kinds of high blood pressure. Metyrosine prevents the tumor from making certain natural substances (catecholamines) that raise the blood pressure and make the heart beat faster. Lowering the amount of catecholamines lessens the risk of a very serious attack of high blood pressure (hypertensive crisis).
Generic name: metyrosine
Pronunciation: (me-TYE-roe-seen)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
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Indications
The following indications are listed for Demser:
- Pheochromocytoma Adjunct Therapy
Also known as: Adjunct Medication Therapy For Pheochromocytoma.
Dosing
No dosing information is available for this tab.
Metyrosine is administered orally.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies using metyrosine have not been performed to date. It is not known whether metyrosine can cause fetal harm when administered to pregnant women. There are no adequate and controlled studies to date using metyrosine in pregnant women. Metyrosine should be used during pregnancy only when clearly needed.
Since it is not known whether metyrosine is distributed into milk, the drug should be used with caution in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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