Tobramycin-Dexamethasone (tobramycin/dexamethasone)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Tobramycin is an aminoglycoside antibiotic.
Dexamethasone is a synthetic fluorinated corticosteroid.
USES: This medication is used to treat or prevent eye infections. This medication contains two drugs. Tobramycin belongs to a class of drugs called aminoglycoside antibiotics.
It works by stopping the growth of bacteria. Dexamethasone belongs to a class of drugs called corticosteroids. It works by reducing swelling.
This medication treats/prevents only bacterial eye infections. It will not work for other types of eye infections. Using any antibiotic when it is not needed can cause it to not work for future infections.
Generic name: tobramycin/dexamethasone
Pronunciation: (TOE-bra-MYE-sin/dex-uh-METH-uh-sown)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Tobramycin-Dexamethasone
Indications
The following indications are listed for Tobramycin-Dexamethasone:
- Ocular Inflammation
- Superficial Ocular Infection
Also known as: Ophthalmic Inflammation, Superficial Ophthalmic Infection.
Dosing
Dexamethasone or its sodium phosphate salt is applied topically to the eye or the ear. Potency of the sodium phosphate preparations is expressed in terms of dexamethasone phosphate. Care should be taken to avoid contamination of the tip of the ointment tube or dropper when the drug is used ophthalmically.
No dosing information is available for this tab.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
There is no enhanced messaging for this drug.
There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
No enhanced messaging available.
No enhanced messaging available.
Animal reproduction studies using systemic tobramycin dosages up to 33 times the usual human systemic dosage have not revealed evidence of impaired fertility or harm to the fetus.
There are no controlled studies to date using tobramycin ophthalmic preparations in pregnant women.
Tobramycin ophthalmic ointment and ophthalmic solution should be used during pregnancy only if clearly needed.
Fixed-combination ophthalmic preparations containing tobramycin and a corticosteroid (i.e., dexamethasone or loteprednol etabonate) should be used during pregnancy only if potential benefits justify potential risks to the fetus.
A decision should be made whether to discontinue nursing or discontinue tobramycin ophthalmic preparations, taking into account the importance of the drug to the woman.
The manufacturers state that caution is advised if fixed-combination ophthalmic preparations containing tobramycin and a corticosteroid are used in nursing women.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
Search health-plan coverage for this drug by ZIP code.
Choose the first character of a health plan name.
Last reviewed · Source: First Databank (FDB) drug data
On this page
Actions
Sign in to save favorites
Saving this drug requires a free Physicians Office Resource account.