Ethambutol Hcl (ethambutol HCl)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Ethambutol hydrochloride is a synthetic antituberculosis agent.
USES: Ethambutol is used with other medications to treat tuberculosis (TB). Ethambutol is an antibiotic and works by stopping the growth of bacteria. This antibiotic treats only bacterial infections.
It will not work for viral infections (such as common cold, flu). Using any antibiotic when it is not needed can cause it to not work for future infections.
Generic name: ethambutol HCl
Pronunciation: (eth-AM-bue-tol)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Ethambutol Hcl
Indications
The following indications are listed for Ethambutol Hcl:
- Active Tuberculosis
- Pulmonary Tuberculosis
Also known as: Active Tb, Acute Tuberculosis, Pulmonary Tb.
Dosing
In patients with impaired renal function, doses and/or frequency of administration of ethambutol hydrochloride should be modified in response to the degree of renal impairment. Some clinicians suggest that if the creatinine clearance is 70-100 mL/minute, dosage of ethambutol hydrochloride should not exceed 15 mg/kg daily, and if the creatinine clearance is less than 70 mL/minute, dosage should be further reduced. Other clinicians have suggested that the usual dose be administered every 24-36 hours in patients with creatinine clearances of 10-50 mL/minute and every 48 hours in patients with creatinine clearances less than 10 mL/minute.
Ethambutol hydrochloride is administered orally.
No dosing information is available for this tab.
No dosing information is available for this tab.
Drug interactions
There is no enhanced messaging for this drug.
There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
There is no enhanced messaging for this drug.
There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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Ethambutol has caused teratogenic effects in animals when used in high doses. Although safe use of the drugs during pregnancy has not been definitely established, ethambutol (combined with isoniazid or with isoniazid and rifampin) has been used to treat clinical tuberculosis in pregnant women and has not been reported to date to cause adverse effects on the fetus The manufacturer states that ethambutol should be used during pregnancy only when the potential benefits justify the possible risks to the fetus. The ATS, CDC, and IDSA state that ethambutol is considered safe for use in pregnant women.
No enhanced messaging available.
No enhanced messaging available.
ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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