Cortisone Acetate (cortisone acetate)
Last reviewed · Source: First Databank (FDB) drug data
Overview
Cortisone is a glucocorticoid secreted by the adrenal cortex.
Cortisone (as the acetate) or hydrocortisone is usually the corticosteroid of choice for replacement therapy in patients with adrenocortical insufficiency, because these drugs have both glucocorticoid and mineralocorticoid properties. Concomitant administration of a more potent mineralocorticoid (fludrocortisone) may be required in some patients. For anti-inflammatory or immunosuppressive uses, synthetic glucocorticoids which have minimal mineralocorticoid activity are preferred.
Generic name: cortisone acetate
Pronunciation: (KOR-ti-sone)
Reference product & biosimilars
No reference, biosimilar or interchangeable associated with this drug.
Today’s intelligence on Cortisone Acetate
Indications
The following indications are listed for Cortisone Acetate:
- Acquired Thrombocytopenia
- Acute Exacerbation Of Multiple Sclerosis
- Acute Gouty Arthritis
- Acute Lymphoid Leukemia
- Acute Rheumatic Carditis
- Adrenocortical Insufficiency
- Adrenogenital Disorder
- Allergic Rhinitis
- Angioedema
- Ankylosing Spondylitis
- Aspiration Pneumonitis
- Atopic Dermatitis
- Autoimmune Hemolytic Anemia
- Berylliosis
- Bursitis
- Congenital Adrenal Hyperplasia
- Contact Dermatitis
- Crohn's Disease
- Dermatitis Herpetiformis
- Diagnostic Test For Cushing's Syndrome
- Diamond Blackfan Anemia
- Disseminated Tuberculosis
- Epicondylitis
- Erythema Multiforme
- Erythroblastic Anemia
- Exfoliative Dermatitis
- Follicular Lymphoma
- Hodgkin's Lymphoma
- Humoral Hypercalcemia Of Malignancy
- Hypersensitivity Drug Reaction
- Idiopathic Thrombocytopenic Purpura
- Inflammatory Bowel Disease
- Juvenile Idiopathic Arthritis
- Loffler Syndrome
- Mycosis Fungoides
- Nephrotic Syndrome
- Non-Hodgkin's Lymphoma
- Ocular Inflammation
- Organ Transplant Rejection
- Pemphigus
- Post Traumatic Osteoarthritis
- Primary Adrenocortical Insufficiency
- Psoriasis
- Psoriatic Arthritis
- Rheumatoid Arthritis
- Sarcoidosis
- Serum Sickness
- Severe Persistent Asthma
- Synovitis
- Synovitis Due To Osteoarthritis
- Systemic Dermatomyositis
- Systemic Lupus Erythematosus
- Tendonitis
- Tenosynovitis
- Thyroiditis
- Trichinosis
Also known as: Aase Syndrome, Acquired Hemolytic Anemia Due To Antibodies, Acute Articular Gout, Acute Exacerbation Of Ms, Acute Gout Attack, Acute Gout Flare, Acute Lymphatic Leukemia, Acute Lymphocytic Leukemia, Acute Lymphogenous Leukemia, Acute Relapse Of Ms, Acute Relapse Of Multiple Sclerosis, Acute Uratic Arthritis, Addison Melanoderma, Adrenal Cortical Hypofunction, Adrenal Failure, Adrenal Insufficiency, Adrenocortical Hypofunction, Adrenogenital Syndrome, Anemia Lymphatica, Angioneurotic Edema, Arthritis Deformans, Arthrosis Deformans, Asthenia Pigmentosa, Atopic Eczema, Atrophedema, Axial Spondyloarthritis With Radiographic Sacroiliitis, Bannister's Disease, Bekhterev's Arthritis, Bekhterev's Disease, Bekhterev's Spondylitis, Besnier-Boeck-Schaumann Disease, Besnier-Boeck-Schaumann Syndrome, Blackfan Diamond Syndrome, Blistering Skin Disease, Boeck's Disease, Boeck's Sarcoid, Bullous Dermatitis Herpetiformis, Chronic Adrenocortical Insufficiency, Congenital Erythroid Hypoplastic Anemia, Congenital Hypoplastic Anemia, Congenital Pure Red Cell Aplasia, Congenital Suprarenal Hyperplasia, Constitutional Erythroid Hypoplasia, Deficiency In Bone Marrow Erythroblasts, Dermatitis Venenata, Diagnostic Procedure For Cushing's Syndrome, Disseminated Lupus Erythematosus, Disseminated Neurodermatitis, Drug Hypersensitivity Reaction, Drug-Induced Hypersensitivity, Drug-Induced Hypersensitivity Reaction, Erythema Exfoliativa, Erythema Polymorphe, Erythroblastopenia, Erythroderma Exfoliativa, Erythrogenesis Imperfecta, Exfoliative Eczema, Exfoliative Erythroderma, Follicular B-Cell Lymphoma, Follicular B-Cell Non-Hodgkin's Lymphoma, Giant Urticaria, Hebra's Disease, Herpes Iris, Hodgkin's Disease, Hypercalcemia Associated With Cancer, Hypercalcemia Associated With Malignancy, Hypercalcemia Of Malignancy, Hypoadrenalism, Hypocorticoidism, Immune Thrombocytopenia, Immune Thrombocytopenia Purpura, Inflammation Of The Synovial Membrane, Inflammation Of The Synovium, Juvenile Ra, Juvenile Rheumatoid Arthritis, Loeffler Syndrome, Loffler's Syndrome, Lupus Erythematosus Syndrome, Lymphoblastic Leukemia, Malignant Hypercalcemia, Marie-Strumpell Disease, Marie-Strumpell Spondylitis, Melasma Addisonii, Mendelson's Syndrome, Miliary Tuberculosis, Milton's Disease, Multiple Sclerosis Exacerbation, Nodose Rheumatism, Non-Hodgkin's Type Lymphoma, Ophthalmic Inflammation, Organ Transplant Rejection Reaction, Periodic Urticaria, Pie Syndrome, Post Infectious Thrombocytopenia, Post Traumatic Oa, Post-Traumatic Osteoarthritis, Posttraumatic Osteoarthritis, Primary Adrenal Deficiency, Primary Adrenal Insufficiency, Primary Corticoadrenal Insufficiency, Primary Failure Adrenocortical Insufficiency, Psoriasis Arthropica, Psoriatic Arthropathy, Purpura Hemorrhagica, Quincke's Disease, Quincke's Edema, Regional Enteritis, Regional Ileocolitis, Rheumatic Arthritis, Rheumatic Gout, Rheumatoid Spondylitis, Rhizomelic Spondylitis, Rhizomelic Spondylosis, Schaumann's Syndrome, Secondary Thrombocytopenia, Serum Sickness-Like Reaction, Simple Pulmonary Eosinophilia, Spondylosis Deformans, Strumpell-Marie Disease, Suprarenal Failure, Synovitis Due To Oa, Synovitis With Osteoarthritis, Tendinitis, Tendinous Synovitis, Tendosynovitis, Tendovaginitis, Tenontolemmitis, Tenontothecitis, Tenovaginitis, Transplant Rejection, Trichinella Spiralis Infection, Trichinellosis, Trichiniasis, Urticaria Tuberosa, Werlhof's Disease.
Dosing
Dosage for infants and children should be based on the severity of the disease and the response of the patient rather than on strict adherence to dosage indicated by age, body weight, or body surface area. After a satisfactory response is obtained, dosage should be decreased in small decrements to the lowest level that maintains an adequate clinical response. Patients should be continually monitored for signs that indicate dosage adjustment is necessary, such as remissions or exacerbations of the disease and stress (surgery, infection, trauma). If cortisone is used orally for prolonged anti-inflammatory therapy, an alternate-day dosage regimen should be considered. Following long-term therapy, cortisone should be withdrawn gradually. (See the Corticosteroids General Statement 68:04.)
The initial adult oral dosage of cortisone acetate may range from 25-300 mg daily depending on the disease being treated. Some clinicians state that children may be given an oral dosage of 0.7-10 mg/kg daily or 20-300 mg/m2 daily in 4 divided doses.
Cortisone acetate is administered orally.
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No dosing information is available for this tab.
Drug interactions
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There are no contraindication interactions for this drug.
There are no severe interactions for this drug.
There are no moderate interactions for this drug.
Contraindications
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There are no contraindication contraindications for this drug.
There are no severe contraindications for this drug.
There are no moderate contraindications for this drug.
Adverse reactions
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There are no severe adverse reactions for this drug.
There are no less severe adverse reactions for this drug.
Precautions
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ICD codes
No ICD codes are available for this drug.
Formulary status
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Last reviewed · Source: First Databank (FDB) drug data
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